Publications by authors named "Huseyin Oktar"
Article Synopsis
- The study looked at how a signaling system called Notch is affected in a liver disease model in rats, and how a substance called resveratrol might help.
- Rats were split into four groups: one that got no treatment, one that received a harmful chemical (CCl₄), one that got the chemical plus resveratrol, and one that got only resveratrol.
- The results showed that the CCl₄ group had more signs of liver damage and higher Notch levels, but the group that received resveratrol had less liver damage and lower Notch levels.
Purpose: To identify expression of Notch signaling proteins and its ligands in human cumulus cells which were obtained by follicle aspiration and to compare the differences of this protein expression between the normal and poor responder patients.
Methods: 47 patients who applied to the assisted reproductive treatments with various infertility problems were included to the study. Controlled ovarian hyperstimulation was performed by using GnRH agonist and gonadotropins.
Hepatic ischemia should be considered in serious liver injury, liver tumor resection and liver transplantation. There are other conditions that decrease hepatic blood flow and cause hepatic ischemia, such as hemorrhagic shock, sepsis, hepatic artery ligation, trauma, and certain vascular lesions. In this study, effects of nimodipine (a calcium channel blocker) and pentoxyfylline (a derivative of methylxanthine) on duration and degree of hepatic ischemia in rats at normothermic and hypothermic conditions are investigated.
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