Publications by authors named "Husam Ouda"

Article Synopsis
  • Pharmacogenomic (PGx) testing is shown to be effective for tailoring cardiovascular disease (CVD) medication dosages, yet it is not routinely included in the UAE healthcare system despite the diverse population.
  • A pilot study with 160 patients analyzed genetic variations related to common CVD drugs, revealing that 46.9% of participants may need alternatives to clopidogrel, and 80% have genetic variants affecting warfarin dosing.
  • The study highlights the potential for implementing PGx-guided therapy in the UAE, emphasizing the importance of personalized medication strategies for better healthcare outcomes.
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Coronary reperfusion strategies for acute ST segment elevation myocardial infarction (STEMI) include primary percutaneous coronary intervention (PCI), intravenous thrombolytic agents and recently mechanical thrombectomy alone during PCI, the latter reserved for those without significant residual disease post-thrombectomy. We describe the success of 'mechanical thrombectomy alone' in two young patients undergoing rescue angioplasty at our institution. Both patients were thrombolysed for inferior STEMI.

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Background: The purpose of this study was to investigate whether endothelial dysfunction contributes to abnormal myocardial perfusion imaging (MPI) observed in patients without obstructive coronary artery disease (CAD). It is unclear whether reversible MPI defects detected in the absence of obstructive CAD represent underlying vascular pathology or are false-positive MPI results. Recent evidence suggests that coronary endothelial dysfunction might play a role in the pathogenesis of these defects.

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Endothelial function can be assessed noninvasively by imaging the brachial artery with ultrasound before and during reactive hyperemia. However, the standard ultrasound equipment typically used for this purpose is limited by size and expense of the machinery. In this study, we compared the ability of a portable ultrasound device to standard ultrasound equipment to visualize the brachial artery for purposes of assessing peripheral vascular endothelial function.

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