The Hydrogen-Bond Continuum in the Salt/Cocrystal Systems of Quinoline and Chloro-Nitrobenzoic Acids.

This study investigates the hydrogen-bond geometry in six two-component solid systems composed of quinoline and chloro-nitrobenzoic acids. New X-ray diffraction studies were conducted using both the conventional independent-atom model and the more recent Hirshfeld atom-refinement method, with the latter providing precise hydrogen-atom positions. The systems can be divided into salts (the hydrogen atom transferred to the quinoline nitrogen), cocrystals (the hydrogen atom retained by the acid), and intermediate structures.

Improved Gas Sensing Capabilities of MoS/Diamond Heterostructures at Room Temperature.

Molybdenum disulfide (MoS) and nanocrystalline diamond (NCD) have attracted considerable attention due to their unique electronic structure and extraordinary physical and chemical properties in many applications, including sensor devices in gas sensing applications. Combining MoS and H-terminated NCD (H-NCD) in a heterostructure design can improve the sensing performance due to their mutual advantages. In this study, the synthesis of MoS and H-NCD thin films using appropriate physical/chemical deposition methods and their analysis in terms of gas sensing properties in their individual and combined forms are demonstrated.

Gas Sensor with Different Morphology of PANI Layer.

This work presents the design of a polymer-film-based sensor for gas detection. Different types of polyaniline are used as active layers. The advantages of resistive sensors with PANI layers are easy preparation and low production cost.

A chemiresistive sensor array based on polyaniline nanocomposites and machine learning classification.

The selective detection of ammonia (NH), nitrogen dioxide (NO), carbon oxides (CO and CO), acetone ((CH)CO), and toluene (CHCH) is investigated by means of a gas sensor array based on polyaniline nanocomposites. The array composed by seven different conductive sensors with composite sensing layers are measured and analyzed using machine learning. Statistical tools, such as principal component analysis and linear discriminant analysis, are used as dimensionality reduction methods.

Disadvantage of the FDM method for printing protective masks against COVID-19 and solution.

Outages in the supply of basic medical supplies and protective equipment have led to efforts to replace them. The team of BUT employees and students has developed a protective half mask that can also be printed on a standard 3D printer without the use of special materials. The original half mask is intended as an improvised protection that can be easily printed on standard 3D printers with FDM technology.

Hydrogen-Terminated Diamond Surface as a Gas Sensor: A Comparative Study of Its Sensitivities.

A nanocrystalline diamond (NCD) layer is used as an active (sensing) part of a conductivity gas sensor. The properties of the sensor with an NCD with H-termination (response and time characteristic of resistance change) are measured by the same equipment with a similar setup and compared with commercial sensors, a conductivity sensor with a metal oxide (MO) active material (resistance change), and an infrared pyroelectric sensor (output voltage change) in this study. The deposited layer structure is characterized and analyzed by Scanning Electron Microscopy (SEM) and Raman spectroscopy.

Dataset of intrusion detection alerts from a sharing platform.

The dataset contains intrusion detection alerts obtained via an alert sharing platform (SABU) for one week. A plethora of heterogeneous intrusion detection systems deployed across several organizations contributed to the sharing platform. The alerts are stored in the intrusion Detection Extensible Alert (IDEA) format and categorized using the eCSIRT.

Erbium ion implantation into diamond - measurement and modelling of the crystal structure.

Diamond is proposed as an extraordinary material usable in interdisciplinary fields, especially in optics and photonics. In this contribution we focus on the doping of diamond with erbium as an optically active centre. In the theoretical part of the study based on DFT simulations we have developed two Er-doped diamond structural models with 0 to 4 carbon vacancies in the vicinity of the Er atom and performed geometry optimizations by the calculation of cohesive energies and defect formation energies.

Erratum: Capecitabine from X-ray powder synchrotron data. Corrigendum.

[This corrects the article DOI: 10.1107/S1600536809017905.].

10-Methyl-isoalloxazine 5-oxide from synchrotron powder diffraction data.

THE TITLE COMPOUND [SYSTEMATIC NAME: 10-methyl-benzo[g]pteridine-2,4(3H,10H)-dione 5-oxide], C(11)H(8)N(4)O(3), consists of a large rigid isoalloxazine group which is approximately planar (r.m.s.

Alaptide from synchrotron powder diffraction data.

THE TITLE COMPOUND [SYSTEMATIC NAME: (8S)-8-methyl-6,9-diaza-spiro-[4.5]decane-7,10-dione], C(9)H(14)N(2)O(2), consists of two connected rings, viz. a piperazine-2,5-dione (DKP) ring and a five-membered ring.

Capecitabine from X-ray powder synchrotron data.

In the title compound [systematic name 5-de-oxy-5-fluoro-N-(pent-yloxycarbon-yl)cytidine], C(15)H(22)FN(3)O(6), the pentyl chain is disordered over two positions with refined occupancies of 0.53 (5) and 0.47 (5).

Methyl-ergometrine maleate from synchrotron powder diffraction data.

The title compound {systematic name: 9,10-didehydro-N-[1-(hydroxy-meth-yl)prop-yl]-d-lysergamide maleate}, C(20)H(26)N(3)O(2) (+)·C(4)H(3)O(4) (-), contains a large rigid ergolene group. This group consists of an indole plane connected to a six-membered carbon ring adopting an envelope conformation and N-methyl-tetra-hydro-pyridine where the methyl group is in an equatorial position. In the crystal, inter-molecular N-H⋯O, O-H⋯N and O-H⋯O hydrogen bonds form an extensive three-dimensional hydrogen-bonding network, which holds the cations and anions together.

Three-dimensional reconstruction of anomalous chloroplasts in transgenic ipt tobacco.

Anomalies in the ultrastructure of chloroplasts, from transgenic ipt tobacco, overproducing endogenous cytokinins (CKs) were studied. Detailed analyses of CKs and their metabolites showed that Pssu-ipt tobacco contained enhanced contents of CKs both in leaves and in isolated chloroplasts. The role of CKs in the formation of anomalous structures is suggested.

Structural characterization of photosystem II complex from red alga Porphyridium cruentum retaining extrinsic subunits of the oxygen-evolving complex.

The structure of photosystem II (PSII) complex isolated from thylakoid membranes of the red alga Porphyridium cruentum was investigated using electron microscopy followed by single particle image analysis. The dimeric complexes observed contain all major PSII subunits (CP47, CP43, D1 and D2 proteins) as well as the extrinsic proteins (33 kDa, 12 kDa and the cytochrome c(550)) of the oxygen-evolving complex (OEC) of PSII, encoded by the psbO, psbU and psbV genes, respectively. The single particle analysis of the top-view projections revealed the PSII complex to have maximal dimensions of 22 x 15 nm.

Polyunsaturated fatty acids stimulate superoxide formation in tumor cells: a mechanism for specific cytotoxicity and a model for tumor necrosis factor?

Some neoplastic cell lines are readily killed when incubated in the presence of polyunsaturated fatty acids (PUFA). In an attempt to elucidate this phenomenon, we studied PUFA-driven superoxide (O2-) production by cultured NS-1 cells (murine lymphoid tumor cells). We find: (1) Even in the absence of added PUFA, NS-1 cells generate O2- (i.

Lymphocyte aggregation in response to adrenergic stimulation.

A nonanemic chronic lymphocytic leukemia patient with nearly 500,000 lymphocytes/microL underwent leukapheresis when she presented with CNS symptoms and retinal vascular engorgement. Respiratory distress developed during the cell separator run, which led us to ask whether the procedure could have changed the adhesive properties of her cells. C5a desarginine, N-f-Met-Leu-Phe, adenosine diphosphate, and collagen all failed to aggregate her lymphocytes in vitro, but arachidonic acid, excess free calcium, and 4 mumol/L epinephrine did aggregate the cells.

Comparison of cefaclor and trimethoprim-sulfamethoxazole in the treatment of acute otitis media.

The efficacy and safety of cefaclor and trimethoprim-sulfamethoxazole (TMP-SMX) were compared in 100 children with acute otitis media assigned to the two treatment groups in a double-blind, randomized fashion. Treatment was for 10 days. Each patient had a diagnostic tympanocentesis before starting therapy.

Evaluation of latamoxef as initial therapy of bone and joint infections in childhood.

The efficacy and pharmacokinetics of latamoxef were evaluated during initial therapy of bacteriologically proven bone and joint infections in children. Pharmacokinetic evaluation revealed no significant difference in latamoxef biodisposition after the first dose or at steady state. Peak serum concentrations exceeded 140 mg/l and 8-hour trough concentrations averaged 6.

Developmental pharmacokinetics of moxalactam.

A pharmacokinetic evaluation of moxalactam was performed with 30 infants and children with documented or suspected bacterial infections arising outside the central nervous system. Each child received 50 mg of moxalactam per kg infused intravenously over a period of 15 min every 8 h. A total of 26 children were studied after receiving the first dose; 20 of these, along with 4 additional patients, were evaluated after receiving continuous therapy for at least 3 days.

Cyclic parenteral nutrition during bone marrow transplantation in children.

Nine children underwent ten bone marrow transplants for malignancies and were supported by parenteral alimentation administered in cyclic fashion 18 hours daily. Children received cyclic parenteral nutrition for an average of 29 days, which provided a caloric intake (mean +/- SD) of 55.9 +/- 18.