Publications by authors named "Hurkul M"

In this study, a new molecularly imprinted polymer (MIP)-based sensor platform was developed for the electrochemical determination of gallic acid (GAL) in plant extracts, wine, and herbal supplements. Gallic acid is known for its natural antioxidant properties, which play an important role in preventing cell deterioration that can lead to various diseases. In addition, gallic acid has therapeutic potential due to its anticancer, antiinflammatory, antimicrobial, and neuroprotective properties.

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This study is the first successful application of a nanomaterial-supported molecularly imprinted polymer (MIP)-based electrochemical sensor for the sensitive and selective determination of apigenin (API), which is a naturally occurring product of the flavone class that is an aglycone of several glycosides. Secondary metabolites are biologically active substances produced by plants in response to various environmental factors. The levels of these compounds can vary depending on factors such as climate, soil conditions and the season in which the plants are grown.

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The escalating costs of healthcare services and a growing awareness of personal health responsibilities have led individuals to explore natural methods alongside conventional medicines for health improvement and disease prevention. The aging global population is experiencing increased health needs, notably related to conditions like diabetes, heart disease, and hypertension. Lifestyle-related diseases, poor dietary habits, and sedentary lifestyles underscore the importance of foods containing nutrients that can aid in preventing and managing these diseases.

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Article Synopsis
  • Quercetin (QUE) is an antioxidant found in various plants and foods, and researchers are focusing on creating sensors to detect it due to its pharmacological importance.
  • A new electrochemical sensor made from a molecularly imprinted polymer (MIP) using tryptophan methacrylate was developed for accurately measuring QUE levels in plant extracts and food products.
  • This sensor demonstrated high sensitivity with a detection limit of 0.235 pM and a useful range of 1.0-25 pM, making it a reliable tool for monitoring QUE in health-related applications.
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Rutin (RUT), a natural flavonoid with various beneficial pharmacological actions such as cardioprotective, antioxidant, anti-inflammatory, neuroprotective, , is found in the content of many plants that are consumed daily. Due to the healthful effects, RUT is also included in the composition of various herbal supplement samples. Therefore, it is highly important to develop a sensor with high selectivity and sensitivity to determine RUT in complex samples.

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Objectives: The genus includes medicinally important plants. Two varieties of have been recorded in Türkiye. Anatomical structures and phytochemical contents are important in the diagnosis and identification of medicinal plants.

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Ethnopharmacological Relevance: The leaves of Michauxia species are used for the treatment of wounds in Turkish traditional medicine. In the present study, wound healing, anti-inflammatory and antioxidant activities of the extracts obtained from the root and herb of 5 species of Michauxia collected in different parts of Turkey were evaluated.

Material And Methods: In vivo incision and excision wound models were used in order to assess the wound healing effects of the methanolic extracts of the plants.

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Context: Several Juniperus species (Cupressaceae) are utilized in folk medicine in the treatment of infections and skin diseases.

Objective: This work was designed to evaluate the antioxidant and antimicrobial potential of methanol and water branches extracts of Juniperus species from Turkey: Juniperus communis L. var.

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