Publications by authors named "Huren Zou"
The rising prevalence of obesity has resulted in an increased demand for innovative and effective treatment strategies. Thunb. has demonstrated promising potential in preventing obesity.
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- The accumulation of CD8 T cells plays a significant role in liver injury and inflammation during metabolic dysfunction-associated steatohepatitis (MASH).
- Empagliflozin (EMPA), a medication that inhibits SGLT2, showed effectiveness in reducing CD8 T cell levels and improving liver conditions in mice with MASH.
- EMPA works by increasing β-hydroxybutyric acid, which inhibits factors that activate CD8 T cells, indicating that targeting these immune cells could be a promising approach for treating MASH in both mice and humans.