High Rates of "Watch" and "Reserve" Class Antibiotics Used to Treat Infections in Neonates and Infants in Southeast Asia.

We evaluated antibiotic prescribing practices for neonates and infants hospitalized with infections in resource-constrained healthcare settings, where antimicrobial resistance is responsible for significant neonatal morbidity and mortality. A point prevalence survey of 667 admitted infants across 10 clinical sites in Southeast Asia revealed a total of 405 antibiotics were prescribed to 218 infants, with high use of World Health Organization-classified "Watch," "Reserve" and "Not Recommended" antibiotics.

Temporal relationships between climate variables and hand-foot-mouth disease: a multi-province study in the Mekong Delta Region, Vietnam.

Hand-foot-mouth disease (HFMD) is an emerging infectious disease that affects thousands of children every year in Vietnam, especially in the Mekong Delta Region (MDR). This study aims to analyse both provincial and regional level effects of climate factors on HFMD in multiple provinces of this high-risk region. Generalized linear models were used to analyse the daily effects of average temperature, humidity and rainfall on HFMD incidence in each province (provincial-level effects), and random-effect meta-analysis was used to estimate the pooled effect size of these climate-HFMD associations (regional-level effects).

The effects of socioecological factors on variation of communicable diseases: A multiple-disease study at the national scale of Vietnam.

Objective: To examine the effects of socioecological factors on multiple communicable diseases across Vietnam.

Methods: We used the Moran's I tests to evaluate spatial clusters of diseases and applied multilevel negative binomial regression models using the Bayesian framework to analyse the association between socioecological factors and the diseases queried by oral, airborne, vector-borne, and animal transmission diseases.

Results And Significance: The study found that oral-transmission diseases were spatially distributed across the country; whereas, the airborne-transmission diseases were more clustered in the Northwest and vector-borne transmission diseases were more clustered in the South.

Spatiotemporal variation of hand-foot-mouth disease in relation to socioecological factors: A multiple-province analysis in Vietnam.

Background: Hand-foot-and-mouth disease (HFMD) is a significant public health issue in Asia-pacific countries. Numerous studies have examined the relationship between socio-ecological factors and HFMD however the research findings were inconsistent. This study examined the association between socio-ecologic factors and HFMD in multiple provinces across Vietnam.

Temporal and spatial analysis of hand, foot, and mouth disease in relation to climate factors: A study in the Mekong Delta region, Vietnam.

This study examined the temporal and spatial patterns of hand, foot, and mouth disease (HFMD) in the Mekong Delta region in Vietnam. A time-series analysis was used to examine the temporal patterns of HFMD in relation to climate factors while a retrospective space-time scan was used to detect the high-risk space-time clusters of this disease. A 1°C increase in average temperature was associated with 5.