Publications by authors named "Hunter J Murdoch"
Article Synopsis
- The study explores how different culture media impact human microglia (hMGL) functions compared to traditional rodent models, revealing that serum-free media can alter their behavior and gene expression.
- Researchers found that adding fetal bovine serum helps maintain important gene functions related to phagocytosis, while growth factors had minimal impact on the transcriptome.
- The results indicate that human microglia in culture have distinct characteristics compared to rodent microglia, highlighting the need for improved models to study their role in health and disease.
