Publications by authors named "Hunter D Evans"
Article Synopsis
- ErbB2 signaling is crucial in breast cancer, influencing its formation and aggressiveness; thus, understanding associated proteins and regulatory factors is important.
- MEMO1, a redox-active protein, interacts with phosphorylated ErbB2 and affects cell movement; researchers developed a fluorescence polarization assay to study this relationship.
- The binding interaction is pH-dependent and strengthened by longer peptides, with key findings showing that phosphorylation is necessary for binding and identifying specific residues important for these interactions, paving the way for future studies on MEMO1 modulators.
