Publications by Hungchan O

Publications by authors named "Hungchan O"

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Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer.

JuHee Sim Woongsik Nam Doohyun Lee Suyoun Lee Hungchan O

Arch Pharm Res

February 2016

Cytochrome P450 (CYP) is an important enzyme that can act on xenobiotic substances such as toxic chemicals or drugs. Phenobarbital (PB) has been widely used to induce CYP2B activity to investigate the drug-drug interaction of CYP2B substrate drugs. Leelamine is a diterpene compound, and is the current focus of efforts to develop a treatment for diabetes.

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