Publications by authors named "Hung-Hao Fan"
Article Synopsis
- The yqiC gene in Salmonella enterica serovar Typhimurium is essential for colonizing human cells and regulates various genes related to pathogenicity and metabolism, but its specific role in nontyphoidal Salmonella interactions is still unclear.
- RNA sequencing of ΔyqiC and wild-type strains revealed that yqiC influences the expression of genes involved in pathogenicity islands, electron transport chains, and energy metabolism, such as ATP generation and glycolysis.
- The results showed that yqiC not only represses some gene expressions but is crucial for the expression of key operons and metabolic functions, indicating its significant role in Salmonella's ability to thrive under energy stress conditions.
Rationale: Anorexia nervosa (AN) is a serious eating disorder associated with a distorted body image. Hypercholesterolemia has been found in patients with AN but the mechanism of hyperlipidemia in AN remains little known. Ascites in patients with AN has been attributed to hypoalbuminemia and liver diseases, but massive ascites without the aforementioned etiologies has never been reported in AN.
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