Publications by authors named "Hung K"
Background: Angelica L. sensu lato is a taxonomically complex genus, and many studies have utilized morphological and molecular features to resolve its classification issues. In Taiwan, there are six taxa within Angelica, and their taxonomic treatments have been a subject of controversy.
View Article and Find Full Text PDFAssociation between high-dose molnupiravir and COVID-19 mortality rate.
Int J Antimicrob Agents
March 2024
Acne keloidalis is a primary scarring alopecia characterized by longstanding inflammation in the scalp causing keloid-like scar formation and hair loss. Histologically, acne keloidalis is characterized by mixed leukocytic infiltrates in the acute stage followed by a granulomatous reaction and extensive fibrosis in the later stages. To further explore its pathogenesis, bulk RNA sequencing, single-cell RNA sequencing, and spatial transcriptomics were applied to occipital scalp biopsy specimens of lesional and adjacent no-lesional skin in patients with clinically active disease.
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- This study examined how underweight patients with COVID-19 fared compared to normal-weight patients and how antiviral treatments affected their outcomes.
- Using a data network, researchers divided the patients into groups to compare hospitalization and death rates during a follow-up period.
- Findings revealed that underweight patients had a higher risk of severe outcomes, but those who received antiviral treatments had significantly better outcomes than those who did not.*
Background/aim: Lenvatinib, an oral multikinase inhibitor, has demonstrated promising activity in patients with osteosarcoma (OS). Therefore, it is worth exploring the inhibitory efficacy and mechanism of action of lenvatinib in osteosarcoma. The primary goal of this study was to examine the inhibitory effectiveness and mechanism of lenvatinib on the growth and invasion of OS cells.
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- The Bentall procedure is a common surgical treatment for aortic root issues, but there's limited research comparing long-term outcomes of bioprosthetic and mechanical valves used during the procedure.
- A study analyzed data from 1052 patients who chose either bioprosthetic (33.4%) or mechanical (66.6%) valves, focusing on overall mortality rates.
- Results showed no significant differences in hospital mortality or long-term survival between the two valve types, suggesting that bioprosthetic valves could be a good option for patients over 50 years old.
Background: Postoperative infectious complications (PICs) are major concerns. Early and accurate diagnosis is critical for timely treatment and improved outcomes. Presepsin is an emerging biomarker for bacterial infections.
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- Ritlecitinib, a treatment for moderate-to-severe ulcerative colitis, shows promise based on a study that evaluated serum and microbiome markers to predict treatment efficacy.
- Researchers analyzed blood and fecal samples from participants before and after 8 weeks of ritlecitinib therapy to identify specific biomarkers associated with patient responses.
- Findings revealed that certain blood proteins and microbiome characteristics can effectively predict clinical outcomes, suggesting potential for personalized treatment strategies in ulcerative colitis management.