Biocompatibility of nanocomposites used for artificial conjunctiva: in vivo experiments.

Purpose: To evaluate the biocompatibility of nanocomposites used for artificial conjunctiva.

Methods: Fifty New Zealand white rabbits were used for the experiments. Nanocomposites of poly -caprolactone (PCL) and of PCL coated with polyvinyl alcohol (PCL+PVA), polyvinyl pyrrolidone (PCL+PVP), or chitosan (PCL+C), and amniotic membrane (AM) as a control, were cut into small disks with a diameter of 3.