Publications by authors named "Humberto Zea Diaz"
Background Blood pressure is determined by the interactions between the heart and arterial properties, and subjects with identical blood pressure may have substantially different hemodynamic determinants. Whether arterial hemodynamic indices quantified by impedance cardiography ( ICG ), a simple operator-independent office procedure, independently predict all-cause mortality in adults from the general population, and specifically among those who do not meet criteria for American College of Cardiology/American Heart Association stage 2 hypertension, is currently unknown. Methods and Results We studied 1639 adults aged 18 to 80 years from the general population.
View Article and Find Full Text PDFNormative values and correlates of carotid artery intima-media thickness and carotid atherosclerosis in Andean-Hispanics: The Prevencion Study.
Atherosclerosis
August 2010
Objectives: Carotid intima-media thickness (cIMT) is an independent predictor of cardiovascular risk. Furthermore, ethnicity and gender-specific normative data are required to assess cIMT, which are not available for Andean-Hispanics. In addition, data regarding correlates of subclinical atherosclerosis in ethnic population are needed.
View Article and Find Full Text PDFObjective: We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults.
Research Design And Methods: Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD).
Results: Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively.
Article Synopsis
- - The study aimed to assess the prevalence of lifestyle-related cardiovascular risk factors among adults in Arequipa, Peru, focusing on behaviors like smoking, alcohol consumption, physical inactivity, and diet.
- - Researchers analyzed data from 1,878 participants, revealing that smoking rates were significantly higher in men (31.1%) compared to women (12.1%), and men also had higher rates of current alcohol use (55.5% vs. 19.7%) and binge drinking (36.1% vs. 6.4%).
- - With over half of the population being insufficiently active and many consuming high-fat diets and low amounts of fruits and vegetables, the findings highlight an urgent need for preventive health programs to
Endogenous NO synthase inhibitors (end-NOSIs) have been associated with cardiovascular risk factors and atherosclerosis. In addition, end-NOSIs may directly cause hypertension through hemodynamic effects. We aimed to examine the association between end-NOSI asymmetrical dimethylarginine (ADMA) and N-guanidino-monomethyl-arginine (NMMA), subclinical atherosclerosis, and arterial hemodynamics.
View Article and Find Full Text PDFArticle Synopsis
- * Among women, low HDL cholesterol and abdominal obesity were the most common MTS components, while men mostly had elevated triglycerides and low HDL cholesterol.
- * The overall prevalence of MTS was higher in women (23.2%) than in men (14.3%), especially increasing with age, indicating a need for further research on underlying causes specific to this population.
Article Synopsis
- Cardiovascular disease is becoming increasingly prevalent in Latin America, with a study of 1,878 Andean adults in Peru revealing a hypertension prevalence of 15.7%, which rises sharply with age, especially among women.
- Awareness, treatment, and control of hypertension were low, with only 47.9% of patients aware of their condition, 39.5% receiving treatment, and a mere 14% achieving effective control.
- The study found that the most common type of hypertension in this population was systodiastolic (41.7%), differing from the U.S. where isolated systolic hypertension is more prevalent, indicating unique genetic and environmental factors influencing hypertension in Andean communities.
Latin America is undergoing the epidemiologic transition that occurred earlier in developed countries, and is likely to face a gigantic epidemic of heart disease in the next few years unless urgent action is taken. The first essential component of any effective cardiovascular disease (CVD) control program is to establish reliable estimates of cardiovascular disease-related morbidity and mortality. However, such data from population-based studies in Latin America are still lacking.
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