Climatic factors associated with economic determinants significantly affect the spread of COVID-19 in tropical Brazil.

Objective: This study investigates the spatial differences in the occurrence of COVID-19 in Brazilian Tropical Zone and its relationship with climatic, demographic, and economic factors based on data from February 2020 to May 2021.

Methods: A Linear Regression Model with the GDP per capita, demographic density and climatic factors from 5.534 Brazilian cities with (sub)tropical climate was designed and used to explain the spread of COVID-19 in Brazil.