Barriers to childhood vaccination in urban slums of Pakistan.

Background: The urban slums of Pakistan continue to record low childhood vaccination coverage. It is therefore vital to understand the demand-side barriers to childhood vaccination in the slums to determine the required demand-generation interventions.

Aims: To document the demand-side barriers related to childhood vaccination in urban slums of Pakistan and recommend appropriate demand-generation interventions.

A Personalized Therapeutics Approach Using an Reveals Optimal Chemo- and Targeted Therapy Combinations for Colorectal Cancer.

models of biomolecular regulation in cancer, annotated with patient-specific gene expression data, can aid in the development of novel personalized cancer therapeutic strategies. is a well-established animal model that is increasingly being employed to evaluate such preclinical personalized cancer therapies. Here, we report five Boolean network models of biomolecular regulation in cells lining the midgut epithelium and annotate them with colorectal cancer patient-specific mutation data to develop an (DPM).