Pathog Glob Health
October 2023
This study examines the effects of three different drugs with metformin, acarbose and pioglitazone active ingredients used for antidiabetic purposes on cysts and trophozoites. Cultures of trophozoites and cysts were prepared to test the anti-amoebic activity of metformin, acarbose and pioglitazone. Cultures were then prepared for cyst and trophozoite forms and parasites were exposed to different concentrations (0.
View Article and Find Full Text PDFAcanthamoeba spp. are free-living amoebae isolated from many ecological areas such as swimming pools, dams and lakes, and soil. Granulomatous amebic encephalitis and amebic keratitis, caused by Acanthamoeba spp.
View Article and Find Full Text PDFBackground: Postoperative epidural adhesion is a frequent cause of failed back surgery syndrome, manifesting with back and leg pain or neurologic deficits. Development of preventive measures for epidural adhesion after laminectomy is critical to improve outcomes of lumbar surgery. We hypothesized that positive effects of topical application of Contractubex (CTX) gel and benzothiazole (BT) individually and in combination could aid in preventing epidural fibrosis in a rat laminectomy model.
View Article and Find Full Text PDFBackground: Grapes and their products are known to have been used for the treatment of diseases throughout history.
Objective: It was aimed to investigate the effects of Erzincan Cimin grapes on an organism model of N2 wild type and BS913 strains with gonad cancer.
Materials And Methods: The effects of methanol extracts of the skin and seeds of Erzincan Cimin grapes were examined separately on N2 wild type and an effect was determined on lifespan.