Bromide accelerates oxidation of selenite by unactivated peroxymonosulfate: PH-dependent kinetics, mechanism and pathways.

Selenium (Se) is an essential trace element that is toxic to humans in a relatively small excess. In natural waters it occurs mainly in inorganic form as Se(IV) and Se(VI) oxyanions with the former being more toxic at high levels. With the increasing use of advanced oxidation processes in drinking water treatment, the oxidation of Se(IV) with unactivated peroxymonosulfate (PMS) has been investigated, but the role of bromide (Br) on the oxidation of Se(IV) during reaction with unactivated PMS remains unknown.

Revealing the impact of sample enrichment method on concentration and cytotoxicity of volatile disinfection byproducts in drinking water: A quantitative study for liquid-liquid extraction.

Liquid-liquid extraction (LLE) combined with the N blow-down method is a promising tool for bioanalysis of drinking water. However, detailed information on which disinfection byproduct (DBP) classes are retained in LLE extracts is currently unavailable. In this study, the recovery of seven classes of volatile DBPs and total adsorbable organic halogens (TOX) during the LLE method, combined with three common N blow-down methods, for bioanalysis in real tap water was analyzed at a 2-L scale, along with their corresponding cytotoxicity.

Removal of particulate matter and dissolved organic matter from sedimentation sludge water during pre-sedimentation process: Performances and mechanisms.

Sedimentation sludge water (SSW), a prominent constituent of wastewater from drinking water treatment plants, has received limited attention in terms of its treatment and utilization likely due to the perceived difficulties associated with managing SSW sludge. This study comprehensively evaluated the water quality of SSW by comparing it to a well-documented wastewater (filter backwash water (FBW)). Furthermore, it investigated the pollutant variations in the SSW during pre-sedimentation process, probed the underlying reaction mechanism, and explored the feasibility of employing a pilot-scale coagulation-sedimentation process for SSW treatment.

Quenching residual HO from UV/HO with granular activated carbon: A significant impact of bicarbonate.

UV/HO has been used as an advanced oxidation process to remove organic micropollutants from drinking water. It is essential to quench residual HO to prevent increased chlorine demand during chlorination/chloramination and within distribution systems. Granular activated carbon (GAC) filter can quench the residual oxidant and eliminate some of the dissolved organic matter.

Adsorption, boiling or membrane filtration for disinfection by-product removal: How to make our drinking water safer?

Disinfection by-products (DBPs) generated in drinking water have become a global concern due to their potential harm to human health. Nevertheless, there are few studies about different point-of-use water treatments in household drinking water. The study aims to compare the effectiveness of three point-of-use water treatments: adsorption, boiling, and membrane filtration.

Accelerated degradation of micro-pollutant by combined UV and chlorine dioxide: Unexpected inhibition of chlorite formation.

UV/chlorine dioxide (ClO) process can be intentionally or accidently conducted and is potentially effective in micro-pollutants degradation. UV irradiation can promote ClO decay and subsequently result in the formation of reactive radicals. Hence, the co-exposure of ClO and UV exhibited a synergetic effect on metribuzin (MET) degradation.

Ethanol-diluted turbidimetry method for rapid and accurate quantification of low-density microplastics in synthetic samples.

Retention and transport behaviours of microplastics (MPs) and their associated pollutants in porous media are of great concern. The homogeneity of the studied MPs in artificially controlled lab-scale studies makes rapid and accurate MP quantification feasible. In this study, an economical ethanol-diluted turbidimetry method for polypropylene (PP) and polyethylene (PE) MPs was developed.

Transformation of Algal Toxins during the Oxidation/Disinfection Processes of Drinking Water: From Structure to Toxicity.

With the increase of algal blooms worldwide, drinking water resources are threatened by the release of various algal toxins, which can be hepatotoxic, cytotoxic, or neurotoxic. Because of their ubiquitous occurrence in global waters and incomplete removal in conventional drinking water treatment, oxidation/disinfection processes have become promising alternative treatment options to destroy both the structures and toxicity of algal toxins. This Review first summarizes the occurrence and regulation of algal toxins in source water and drinking water.

Formation and transformation of pre-chlorination-formed disinfection byproducts in drinking water treatment process.

As pre-chlorination is increasingly adopted in drinking water treatment plant (DWTP), an attractive question emerged: how the disinfection by-products that formed during pre-chlorination (preformed DBPs) would be transformed in the drinking water treatment process? This study investigated the DBP formation kinetics and molecular characteristics in chlorinated source water, DBP transformation and removal in practical DWTP. It was found that the formation of trihalomethanes (THMs) followed pseudo first-order kinetic model and the intensified Br exposure facilitated the transformation of TCM into TBM. As Br concentration shifted from 0.

Unravelling High-Molecular-Weight DBP Toxicity Drivers in Chlorinated and Chloraminated Drinking Water: Effect-Directed Analysis of Molecular Weight Fractions.

As disinfection byproducts (DBPs) are ubiquitous sources of chemical exposure in disinfected drinking water, identifying unknown DBPs, especially unknown drivers of toxicity, is one of the major challenges in the safe supply of drinking water. While >700 low-molecular-weight DBPs have been identified, the molecular composition of high-molecular-weight DBPs remains poorly understood. Moreover, due to the absence of chemical standards for most DBPs, it is difficult to assess toxicity contributions for new DBPs identified.

Simple and Sensitive Method for Synchronous Quantification of Regulated and Unregulated Priority Disinfection Byproducts in Drinking Water.

Due to their elevated concentrations in drinking water, compared to other emerging environmental contaminants, disinfection byproducts (DBPs) have become a global concern. To address this, we have created a simple and sensitive method for simultaneously measuring 9 classes of DBPs. Haloacetic acids (HAAs) and iodo-acetic acids (IAAs) are determined using silylation derivatization, replacing diazomethane or acidic methanol derivatization with a more environmentally friendly and simpler treatment process that also offers greater sensitivity.

Priority screening of contaminants of emerging concern in drinking water sources of eastern China: Assessing risks based on exposure-activity ratios (EARs).

Increasing and widely detected contaminants of emerging concern (CECs) pose a threat to drinking water safety. Compared with traditional methods, the exposure-activity ratio (EAR) method based on the ToxCast database may have unique advantages in risk assessment of drinking water sources because it provides massive multi-target high-throughput screening toxicity effect data assessment for chemicals with missing traditional toxicity data. In this study, 112 CECs at 52 sampling sites in drinking water sources in Zhejiang Province of eastern China were investigated.

Enzalutamide and olaparib synergistically suppress castration-resistant prostate cancer progression by promoting apoptosis through inhibiting nonhomologous end joining pathway.

Recent studies revealed the relationship among homologous recombination repair (HRR), androgen receptor (AR), and poly(adenosine diphosphate-ribose) polymerase (PARP); however, the synergy between anti-androgen enzalutamide (ENZ) and PARP inhibitor olaparib (OLA) remains unclear. Here, we showed that the synergistic effect of ENZ and OLA significantly reduced proliferation and induced apoptosis in AR-positive prostate cancer cell lines. Next-generation sequencing followed by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses revealed the significant effects of ENZ plus OLA on nonhomologous end joining (NHEJ) and apoptosis pathways.

Perfluorinated compound correlation between human serum and drinking water: Is drinking water a significant contributor?

Perfluorinated compounds (PFASs) are a new artificial chemical. Due to its substantial toxicity and complex degradation in the natural environment, monitoring PFASs has become a hot issue for many researchers. Currently, the relationship between the concentration of PFASs in serum and the concentration of PFASs in drinking water is unclear.

Overlooked Iodo-Disinfection Byproduct Formation When Cooking Pasta with Iodized Table Salt.

Iodized table salt provides iodide that is essential for health. However, during cooking, we found that chloramine residuals in tap water can react with iodide in table salt and organic matter in pasta to form iodinated disinfection byproducts (I-DBPs). While naturally occurring iodide in source waters is known to react with chloramine and dissolved organic carbon (e.

Interactions between HO and dissolved organic matter during granular activated carbon-based residual HO quenching from the upstream UV/HO process.

Granular activated carbon (GAC) filtration can be employed to synchronously quench residual HO from the upstream UV/HO process and further degrade dissolved organic matter (DOM). In this study, rapid small-scale column tests (RSSCTs) were performed to clarify the mechanisms underlying the interactions between HO and DOM during the GAC-based HO quenching process. It was observed that GAC can catalytically decompose HO, with a long-lasting high efficiency (>80% for approximately 50,000 empty-bed volumes).

Trigred motif 36 regulates neuroendocrine differentiation of prostate cancer via HK2 ubiquitination and GPx4 deficiency.

Neuroendocrine prostate cancer (NEPC), the most lethal subtype of castration-resistant prostate cancer (PCa), may evolve from the neuroendocrine differentiation (NED) of PCa cells. However, the molecular mechanism that triggers NED is unknown. Trigred motif 36 (TRIM36), a member of the TRIM protein family, exhibits oncogenic or anti-oncogenic roles in various cancers.

[Occurrence and Health Risk Assessment of Multiple Pesticides in Drinking Water Sources of Southeast China].

To elucidate the pollution characteristics and ecological risks of pesticide micro-pollutants in typical drinking water sources in Southeast China, the detection frequency, detection concentration, and risk quotient of each pesticide for three different trophic levels of organisms (green algae, daphnia, and fish) were analyzed for a total of 55 commonly used pesticides in 19 categories, including benzimidazoles, amides, triazoles, and organophosphates, in seven reservoirs in Southeast China. Among the 55 pesticides analyzed, two pesticides (carbendazim and acetochlor) had a detection frequency of 100%, and 12 pesticides had a detection frequency of 80% or more. The highest detection concentration was found for carbendazim (77.

Accelerated transformation of sodium dodecylbenzene sulfonate surfactant in the UV/chlorine process: Kinetics and formation of chlorinated disinfection by-products.

The degradation kinetics of Sodium dodecylbenzene sulfonate (SDBS) surfactant in the UV/chlorine process was comprehensively investigated, and the formation of chlorinated disinfection by-products (Cl-DBPs) were determined. Results showed that the degradation of SDBS by UV, chlorine and UV/chlorine all followed pseudo-first-order kinetics. The rate constant by UV/chlorine in ultrapure water was approximately 3 times higher than the sum of those by UV and chlorine, and decreased from 0.

Revisiting the effect of boiling on halogenated disinfection byproducts, total organic halogen, and cytotoxicity in simulated tap water.

Boiling is a widely adopted household tap water treatment method because of its ability to inactivate chlorine-resistant pathogenic bacteria, and to reduce certain groups of disinfection byproducts (DBPs). From a more comprehensive point of view, this study revisited the effect of boiling on four groups of 17 aliphatic DBPs and six groups of 44 aromatic DBPs in both simulated chlorinated and chloraminated tap water samples, with a special focus on the changes of total organic halogen (TOX) and cytotoxicity. Results showed that the concentrations of aliphatic DBPs substantially decreased during boiling via volatilization (trihalomethanes and chloral hydrate) and hydrolysis (haloacetamides) in chlorinated and chloraminated tap water samples.

Coupling methanotrophic denitrification to anammox in a moving bed biofilm reactor for nitrogen removal under hypoxic conditions.

Simultaneous removal of ammonium and nitrate was achieved in a methane-fed moving bed biofilm reactor (MBBR). In the reactor, methanotrophic microorganisms oxidized methane under hypoxic conditions likely to methanol, hence providing an electron donor to denitrifiers to reduce nitrate to nitrite that then allowed anaerobic ammonium oxidizing bacteria (Anammox) to remove excess ammonium as N. The ammonium and nitrate removal rates reached 72.

Simultaneous oxidation of trace organic contaminant and Mn(II) by Mn(VII): Accelerating role of dissolved oxygen.

Permanganate (Mn(VII)) is a widely used oxidant in water treatment, which can oxidize trace organic contaminants (TrOCs) and Mn(II). Interestingly, this study found that presence of Mn(II) could accelerate the abatement of bisphenol A by Mn(VII) only under oxic condition. Herein, the effects of Mn(II) and dissolved oxygen (DO) on the abatement of TrOCs by Mn(VII) oxidation and the related mechanism were investigated.