Influence of effective decay constant uncertainty on radon exhalation rate measurement from medium surfaces using CR-39.

The CR-39 solid-state nuclear track detector is a commonly used instrument for passively measuring radon. When using CR-39 to measure the radon exhalation rate from the surface of a medium, the effects of leakage are often overlooked. However, to a certain extent, system leakage can affect the accuracy of the measurement results.

Correction: Du et al. Extraction Condition Optimization, Quantitative Analysis, and Anti-AD Bioactivity Evaluation of Acorn Polyphenols from , , and . 2024, , 10536.

In the original publication [...

Long non-coding RNA LINC01232 promotes malignancy of prostate cancer through regulation of miR-181a-5p/IRS2 pathway: Ki-67 protein molecular structure and function.

The expression level of long non-coding RNA (lncRNA), which functions in a manner similar to that of microrNA, has been confirmed to be closely associated with the regulatory network of multiple cancers. The primary focus of this particular research endeavor was to elucidate the mechanism of action of LINC01232 within the context of prostate cancer, specifically examining how it influences the proliferation of prostate cancer cells by interacting with the miR-181a-5p/IRS2 pathway. Additionally, the study aimed to delve deeper into the role of the Ki-67 protein within this intricate process.

Vitamin A treatment restores vision failures arising from Leber's hereditary optic neuropathy-linked mtDNA mutation.

Leber hereditary optic neuropathy (LHON) is a paradigm for mitochondrial retinopathy due to mitochondrial DNA (mtDNA) mutations. However, the mechanism underlying retinal cell-specific effects of LHON-linked mtDNA mutations remains poorly understood and there has been no effective treatment or cure for this disorder. Using a mice model bearing a LHON-linked ND6P25L mutation, we demonstrated that the mutation caused retinal cell-specific deficiencies, especially in retinal ganglion cells (RGC), rods and Müller cells.

Peony Seed Oil Inhibited Neuroinflammation by PPAR/RXR Signaling Pathway in D-Gal Induced Mice.

Essential fatty acids could regulate inflammation, especially n-3 PUFA (n-3 polyunsaturated fatty acids), which are considered to have a protective effect to inhibit neuroinflammation. Peony seed oil is one of the most abundant n-3 PUFAs in oils. but the mechanism of peony seed oil affecting inflammation in mice brains is still lacking convincing evidence.

The protein Mhp274 elicits mucosal and systemic immune responses in mice.

Background: is the etiological agent of mycoplasmal pneumonia of swine (MPS). Commercial vaccines provide partial protection and do not prevent the colonization and transmission of . The bottleneck in the development of more effective vaccines for MPS is the stimulation of effective immune responses in the host.

Preparation and functional characteristics of starch-lipid complexes with different oleic acid-rich glycerolipids.

Starch-lipid complexes with functional properties have gained extensive attention; however, little attention has been paid to how oleic acid-based lipid types and thermomechanical treatment affect the functional characteristics of starch. This study investigated the effects of five oleic acid-based lipids (oleic acid, monoolein, diolein, triolein, and rapeseed oil) and thermomechanical treatment on the structural and physicochemical properties of wheat starch. The crystal patterns and complexing indices showed that thermomechanical treatment promoted the formation of oleic acid, monoolein, and diolein V-type starch-lipid complexes with an intact granular structure, whereas triolein and rapeseed oil formed complexes with starch.

Advancements in rheumatoid arthritis immunotherapy: a comprehensive bibliometric analysis of research trends and hotspots (2003-2023).

Objectives: To analyse research trends and developments in rheumatoid arthritis (RA) immunotherapy through a comprehensive bibliometric analysis of literature from 2003 to 2023.

Methods: Publications related to RA immunotherapy were retrieved from Web of Science Core Collection database using specified search terms. Bibliometric analysis was performed with VOSviewer, CiteSpace, Pajek, and R packages to examine publication patterns, international collaborations, research hotspots, and emerging trends.

Chemo-proteomics reveals dihydrocaffeic acid exhibits anti-inflammation effects via Transaldolase 1 mediated PERK-NF-κB pathway.

Background: Acute pneumonia is a kind of widespread inflammatory pathological process. Dihydrocaffeic acid (DA), metabolite of chlorogenic acid, possesses potent pharmacologic activity for the therapy of a wide range of disorders and various biological properties, such as anti-inflammation. Nevertheless, the specific protein targets and potential molecular mechanisms of DA in acute pneumonia are still poorly understood.

HER2 positive primary breast squamous cell carcinoma with good prognosis: a case report.

Background: Primary breast squamous cell carcinoma (PBSCC) is a unique histopathological type of breast cancer. The majority of current case reports of PBSCC are triple-negative tumors with poor prognosis. Due to its heterogeneous clinical course, no unified management is achieved.

A large histological images dataset of gastric cancer with tumour microenvironment annotation for AI.

Gastric cancer (GC) is the third leading cause of cancer death worldwide. Its clinical course varies considerably due to the highly heterogeneous tumour microenvironment (TME). Decomposing the complex TME from histological images into its constituent parts is crucial for evaluating its patterns and enhancing GC therapies.

The landscape of immunogenic cell death-related genes predicts the overall survival and immune infiltration status of non-small-cell lung carcinoma.

Background: Non-small cell lung cancer (NSCLC), which accounts for about 85 % of all lung cancers, currently exhibits insensitivity to most treatment regimens. Therefore, the identification of new and effective biomarkers for NSCLC is crucial for the development of treatment strategies. Immunogenic cell death (ICD), a form of regulated cell death capable of activating adaptive immune responses and generating long-term immune memory, holds promise for enhancing anti-tumor immunity and offering promising prospects for immunotherapy strategies in NSCLC.

Effect of Residue Feed on Immunity, Antioxidant Capacity, and Transcriptome in Chickens: A Study on Sanhuang Chickens.

This study investigated the effects of residue (PAR) on the immune function, antioxidant capacity, and transcriptome of Sanhuang chickens. Six hundred 30-day-old Sanhuang chickens were divided into six groups with diets of varying PAR replacement of soybean meal from 0 to 100% in increments of 20%. Samples were taken on day 100.

Yanghe decoction alleviates osteoarthritis by AMPK-SIRT3 positive feedback loop-mediated mitochondrial autophagy.

Ethnopharmacological Relevance: Yanghe Decoction(YHD) is a traditional Chinese medicine compound known for its efficacy in treating osteoarthritis (OA).

Aim Of The Study: We aimed to explore the underlying mechanisms of YHD in relation to OA.

Materials And Methods: UHPLC-MS technology was used to identify the material basis of YHD.

Cyanophage Engineering for Algal Blooms Control.

Cyanobacteria represent a prevalent category of photosynthetic autotrophs capable of generating deleterious algal blooms, commonly known as cyanobacteria harmful algal blooms (cyanoHABs). These blooms often produce cyanotoxins, which pose risks to public health and ecosystems by contaminating surface waters and drinking water sources. Traditional treatment methods have limited effectiveness.

Use of the Delphi Method in the Construction of the Temperature Chain Management Scheme for Da Vinci Robot-Assisted Urological Surgical Patients.

The study aimed to construct a temperature chain management scheme in patients undergoing Da Vinci Robot-assisted surgery in urological surgical patients by the Delphi method, providing a reference for the prevention and treatment of the inadvertent perioperative hypothermia. First, instructing by the Joanna Briggs Institute (JBI) Evidence-Based Healthcare model and systematically reviewing literature related to the prevention and treatment of perioperative hypothermia in Da Vinci robot-assisted surgery patients in the urological surgical patients from guideline-related websites and professional association websites. Second, carrying out the qualitative interviews, which were conducted with medical staff in the urology department and the Da Vinci robot-assisted surgery team in a teaching hospital.

Cr-doped NiFe sulfides nanoplate array: Highly efficient and robust bifunctional electrocatalyst for the overall water splitting and seawater electrolysis.

To replace precious metals and reduce production costs for large-scale hydrogen production, developing stable, high-performance transition metal electrocatalysts that can be used in a wide range of environments is desirable yet challenging. Herein, a self-supported hybrid catalyst (NiFeCrS/NF) with high electrocatalytic activity was designed and constructed using conductive nickel foam as a substrate via manipulation of the cation doping ratio of transition metal compounds. Due to the strong coupling synergy between the metal sulfides NiS, FeS, and CrS, as well as their interaction with the conductive nickel foam (NF), the energy barrier for catalytic reactions is reduced, and the charge transfer rate is enhanced.

METTL3-mediated m6A modification promotes chemoresistance of intrahepatic cholangiocarcinoma by up-regulating NRF2 to inhibit ferroptosis in cisplatin-resistant cells.

This study explores the relationship between m6A modification and ferroptosis in intrahepatic cholangiocarcinoma (ICC) and its impact on cisplatin resistance. We established cisplatin-resistant cells. CCK-8 and Transwell assays were conducted to evaluate the effects of METTL3 on drug resistance, migration, and invasion.

A Wide Color Gamut and Noniridescent Zinc-Anode Asymmetric Electrochromic Device for Self-Sustaining Color-Adaptive Bio-Camouflage System.

Inspired by camouflage-colored organisms, the development of bio-camouflage systems using electrochromic (EC) technology has gained significant interest. However, existing EC systems struggle with achieving a wide color gamut, noniridescent colors, and self-sustainability. Herein, a self-sustainable color-adaptive bio-camouflage system integrating EC and nanogenerator (NG) technologies, enabling environmental color adaptation, and thermal regulation without an external power source is proposed.

Extraction Condition Optimization, Quantitative Analysis, and Anti-AD Bioactivity Evaluation of Acorn Polyphenols from and .

In the present study, and acorn kernels were taken as the research objects, and the free polyphenols and bound polyphenols in acorn kernels were extracted using improved ultrasound-assisted ethanolic and alkaline extraction methods, after which the contents of gallic acid, quercetin, azelaic acid, ellagic acid, and ferulic acid were quantified by LC-MC/MS. The results demonstrated that and acorns were suitable as raw materials to extract ellagic acid, the contents of ferulic acid and bound gallic acid in them were different, and acorns were more suitable for the research of gallic acid, but not for azelaic acid. Results on APP/PS1 transgenic mice verified that five polyphenols significantly suppressed the progression of AD.