Equol Alleviates the In Vitro Aging-Induced Disruption of Porcine Oocytes.

Oocyte quality is crucial for determining the subsequent embryo developmental capacity and reproductive outcomes. However, aging is detrimental to oocyte quality. Previous studies have demonstrated that soy isoflavones have positive effects on the reproductive performance of female pigs.

MALDI-TOF Mass Spectrometry Reveals the Effect of Acetyl-L-Carnitine on the Lipid Profile of Buffalo Oocytes and Cumulus Cells During In Vitro Maturation.

Lipids in cumulus-oocyte complexes are important actors in molecular signalling pathways and are influenced by maturation conditions. Acetyl-L-carnitine (ALC) is a carrier involved in fatty acid transport and is a promoter of β-oxidation. Although the embryonic development potential of oocytes can be improved when ALC is added to the maturation medium, the effects of ALC on the lipid content and composition of oocytes and cumulus cells remain unknown.

Oxidative phosphorylation decline and mitochondrial dynamics disequilibrium are involved in chicken large white follicle atresia.

In domestic hens, the atresia of large white follicles (LWFs) directly affects the number of follicles that enter the hierarchical development and ovulation. Figuring out factors responsible for LWFs atresia is helpful to improve egg production of hens. At the LWF stage, yellow yolk begins to be deposited into the follicles via receptor mediated endocytosis, which requires large amounts of ATP.

Wild sympatric rodents inhabiting pig farm environments may facilitate the spillover of Enterocytozoon bieneusi from pig farms.

Enterocytozoon bieneusi is a zoonotic pathogen prevalent in mammalian and avian hosts across the globe. Wild small mammals, being abundant worldwide, serve as important sources of zoonotic disease transmission to humans. Here, 227 fecal samples were collected from five rodent and shrew species on 34 pig farms in China to investigate the prevalence and molecular characterization of E.

Deep active learning with high structural discriminability for molecular mutagenicity prediction.

The assessment of mutagenicity is essential in drug discovery, as it may lead to cancer and germ cells damage. Although in silico methods have been proposed for mutagenicity prediction, their performance is hindered by the scarcity of labeled molecules. However, experimental mutagenicity testing can be time-consuming and costly.

Coordination Compound Guided a Novel Composite Film with ZnVO Nanoflake and VO@ZnVO Nanoparticle for Enhanced Thermochromism Smart Window.

Thermochromic vanadium dioxide (VO) can intelligently modulate the transmittance of indoor solar radiation to reduce the energy consumption of air conditioning in buildings. Nevertheless, it remains a great challenge to simultaneously improve the luminous transmittance (T) and solar modulation ability (ΔT) of VO. In this study, a novel approach is employed utilizing a coordination compound to finely tune the growth of a VO based composite film, yielding a hierarchical film comprising ZnVO nanoflakes and VO@ZnVO core-shell nanoparticles.

Impacts of a highly pathogenic ovine Eimeria ovinoidalis on the growth of Hu lambs.

The apicomplexan Eimeria ovinoidalis is distributed worldwide. It can cause clinical coccidiosis, which is one of the most pathogenic species in sheep, reducing growth rates and resulting in significant economic losses in the industry. Its principal clinical sign is profuse diarrhoea in young animals.

Proteomic and antimicrobial peptide analyses of Buffalo colostrum and mature Milk whey: A comparative study.

Buffalo colostrum is the initial mammary secretion after parturition, consisting of nutritional and bioactive components. In this study, we conducted a proteomic analysis of buffalo colostrum whey to identify bioactive proteins and peptides. A total of 107 differentially expressed proteins (DEPs) were identified in buffalo colostrum whey compared to those in mature milk.

Occurrence and genotypic identification of Blastocystis sp., Enterocytozoon bieneusi, and Giardia duodenalis in dairy cattle in Heilongjiang Province, China.

Blastocystis sp., Enterocytozoon bieneusi, and Giardia duodenalis are three common zoonotic intestinal parasites, and cattle are important hosts of these three intestinal protozoa. In this study, 1632 fecal samples were collected from dairy farms in Heilongjiang Province, China, and screened for Blastocystis sp.

Mogroside V alleviates the heat stress-induced disruption of the porcine oocyte in vitro maturation.

Heat stress (HS) is a stressor that negatively affect female reproduction. Specially, oocytes are very sensitive to HS. It has been demonstrated that some active compounds can protect oocyte from HS.

Metagenomic analysis of gut microbiome and resistome of Whooper and Black Swans: a one health perspective.

Background: With the promotion of "One Health," the health of animals and their impact on the environment have become major concerns recently. Widely distributed in China, the whooper swans (Cygnus cygnus) and black swans (Cygnus atratus) are not only important to the ecological environment, but they may also potentially influence public health security. The metagenomic approach was adopted to uncover the impacts of the gut microbiota of swans on host and public health.

A regression model combined convolutional neural network and recurrent neural network for electroencephalogram-based cross-subject fatigue detection.

Fatigue, one of the most important factors affecting road safety, has attracted many researchers' attention. Most existing fatigue detection methods are based on feature engineering and classification models. The feature engineering is greatly influenced by researchers' domain knowledge, which will lead to a poor performance in fatigue detection, especially in cross-subject experiment design.

Metagenomic analysis reveals the relationship between intestinal protozoan parasites and the intestinal microecological balance in calves.

Background: A close connection between a protozoan parasite and the balance of the other gut microbes of the host has been demonstrated. The calves may be naturally co-infected with many parasites, and the co-effects of parasites on other intestinal microbes of calves remain unclear. This study aims to preliminarily reveal the relationship between intestinal parasites and other intestinal microbes in calves.

Prevalence of Cryptosporidium infection in children from China: a systematic review and meta-analysis.

Cryptosporidium is an important zoonotic pathogen that causes diarrhea in humans and animals, and a leading cause of diarrhea morbidity and mortality in children under 5 years old. However, the meta-analysis of Cryptosporidium infection in children in China has not been published. We searched the databases for articles published on the prevalence of Cryptosporidium infection in children in China since the inception of these databases to 31 October 2022.

Global prevalence of spp. in pigs: a systematic review and meta-analysis.

spp. are significant opportunistic pathogens causing diarrhoea in humans and animals. Pigs are one of the most important potential hosts for .

Psychometric validation of the sibling inventory of behavior in three- to six-year-old Chinese children.

With increasing attention on sibling relationship studies in China, one problem that has been neglected is the limited validation of instruments used to assess these relationships. The present study evaluated the psychometric properties of the Sibling Inventory of Behavior to measure Chinese children's sibling relationships using a stratified random sample of 590 parents of three- to six-year-olds in three economic regions. The confirmatory factor analysis obtained an adequate fit, suggesting that the Chinese version of the instrument had a six-factor structure (i.

First identification of Blastocystis sp. subtypes in Rex rabbits in China.

Blastocystis sp. is a common protist that colonizes the intestinal tract in both humans and animals worldwide. A total of 666 fecal samples of Rex rabbits were collected from 12 farms in three administrative regions in Henan, China.

Comparative proteomic analysis of seminal plasma exosomes in buffalo with high and low sperm motility.

Background: Exosomes are nanosized membranous vesicles secreted by various types of cells, which facilitate intercellular communication by transporting bioactive compounds. Exosomes are abundant in biological fluids including semen, and their protein composition and the potential of seminal plasma exosomes (SPEs) as fertility biomarkers were elucidated in humans, however, little information is available regarding buffalo (Bubalus bubalis). Here, we examined protein correlation between spermatozoa, seminal plasma (SP), and SPEs, and we compared and analyzed protein differences between high-motility (H-motility) and low-motility (L-motility) SPEs in buffalo.

Research on improved intestinal image classification for LARS based on ResNet.

Low anterior rectal resection is an effective way to treat rectal cancer at present, but it is easy to cause low anterior resection syndrome after surgery; so, a comprehensive diagnosis of defecation and pelvic floor function must be carried out. There are few studies on the classification of diagnoses in the field of intestinal diseases. In response to these outstanding problems, this research will focus on the design of the intestinal function diagnosis system and the image processing and classification algorithm of the intestinal wall to verify an efficient fusion method, which can be used to diagnose the intestinal diseases in clinical medicine.

Tracking the dynamics of female germ cell development during peri-hatch periods using a gene-edited chicken model.

In hens, egg production depends on the development of germ cells in the ovary. Germ cells are established before birth, and their number gradually decreases during their lifespan. Therefore, it is essential to determine the time points of massive germ cell loss and the underlying mechanism.

The complement C3a-C3aR and C5a-C5aR pathways promote viability and inflammation of human retinal pigment epithelium cells by targeting NF-κB signaling.

Retinal detachment (RD) and its special form of rhegmatogenous RD associated with choroidal detachment (RRDCD) feature similar pathological alterations, including enhanced retinal cell inflammation. Although the importance of the complement components C3a and C5a and their corresponding receptors in retinal maintenance has been demonstrated, the relevance of these molecules to the pathogenesis of RD or RRDCD remains to be investigated. The contents of C3a, C5a and inflammatory factors, such as TNF-α, IL-1β, IL-6 and prostaglandin (PG)E2, in related clinical samples were examined by ELISA.

(), a Novel Reduced-Height () Gene in Wheat.

In wheat, a series of dwarf and semi-dwarf plant varieties have been developed and utilized worldwide since the 1960s and caused the 'Green Revolution'. To date, 25 reduced-height () genes have been identified, but only several genes for plant height (PH) have been isolated previously. In this study, we identified a candidate gene, (), for PH via QTL mapping and genome-wide association study (GWAS) methods.