Persistent organic pollutants and metabolic diseases: From the perspective of lipid droplets.

The characteristic of semi-volatility enables persistent organic pollutants (POPs) almost ubiquitous in the environment. There is increasing concern about the potential risks of exposure to POPs due to their lipophilicity and readily bioaccumulation. Lipid droplets (LDs) are highly dynamic lipid storage organelles, alterations of intracellular LDs play a vital role in the progression of many prevalent metabolic diseases, such as type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD).

Comparing the efficacy and safety of tenofovir and adefovir or combined drug treatment for the treatment of chronic hepatitis B infection: a systematic review and meta-analysis.

Background: Chronic hepatitis B (CHB) affects a vast population globally. A variety of drugs are available for the treatment of CHB, including tenofovir (TDF) and adefovir (ADV). However, the efficacy of monotherapy drug treatment is inconclusive, the safety and efficacy of TDF remain unclear, more data are needed to be included and combined drug treatment is considered to exhibit higher efficacy.

Effects of vegetation cover and slope on soil erosion in the Eastern Chinese Loess Plateau under different rainfall regimes.

Soil erosion is a critical environmental problem of the Chinese Loess Plateau (CLP). The effects of vegetation cover on soil erosion reduction under different rainfall types are not well understood especially in the eastern Chinese Loess Plateau (ECLP). In this study, we monitored runoff and sediment yield at the Fengjiagou water and soil conservation station with five types of vegetation cover (arbor trees (ARC), shrubs (SHC), arable (ABC), natural vegetation (NVC), and artificial grass (APC)) and three slope gradients (10°, 15°, and 20°) in the ECLP.