Measurement of BAT activity by targeted molecular magnetic resonance imaging.

Objective: The aim of this study was to measure brown adipose tissue (BAT) activity by targeted peptide (CKGGRAKDC-NH2)-coupled, polyethylene glycol (PEG)-coated ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles with magnetic resonance imaging (MRI).

Methods: The peptide was conjugated with PEG-coated USPIO to obtain targeted probes. Male C57BL/6 J mice were randomly divided into cold exposing and control group (n = 5 per group).

Parathyromatosis type 2 detected by Tc-MIBI SPECT/CT.

Parathyromatosis, which is defined as multiple foci of benign hyperfunctioning parathyroid tissue in neck or mediastinum, is a rare but severe cause of persistent/recurrent renal hyperparathyroidism (rHPT) after parathyroidectomy (PTX). It is hard to detect and remove all the foci. We present a case of parathyromatosis in a haemodialysed patient, who had three PTXs for persistent/recurrent rHPT and was free of recurrence during 31-month follow-up after the third PTX.