Publications by authors named "Huisha Du"
Article Synopsis
- Norovirus (NoV), especially the GII.4 and GII.17 strains, is a leading cause of viral gastroenteritis, making quick and accurate detection crucial for responding to outbreaks.
- The study developed a method using recombinase-aided amplification and CRISPR-Cas13a technology that allows for the detection of these NoV strains within 40 minutes using a simple setup and can be visually interpreted without specialized equipment.
- The new detection method demonstrated impressive sensitivity (97.96%) and specificity (100%), with a low detection limit, making it a cost-effective option for low-resource areas, contributing to better public health management and response strategies against NoV outbreaks.
Introduction: Herd immunity against norovirus (NoV) is poorly understood in terms of its serological properties and vaccine designs. The precise neutralizing serological features of genotype I (GI) NoV have not been studied.
Methods: To expand insights on vaccine design and herd immunity of NoVs, seroprevalence and seroincidence of NoV genotypes GI.