ZC3H13 Enhances the Malignancy of Cervical Cancer by Regulating m6A Modification of CKAP2.

Sustained expression of zinc finger CCCH-type containing 13 (ZC3H13) in tumors is essential for cancer cell malignancy; however, our understanding of its clinical effects and mechanisms in cervical cancer (CC) is limited. In this study, we aimed to reveal the effect on CC progression of ZC3H13-mediated N6-methyladenosine (m6A) modification to stabilize cytoskeleton-associated protein 2 (CKAP2) expression. CC tissues and paired adjacent normal tissues were collected from 50 patients.

Sexual Dimorphism in the Chinese Endemic Species (Urodela: Hynobiidae).

Sexual dimorphism is common in most vertebrate species and has diverse manifestations. The study of sexual dimorphism has critical significance for evolutionary biological and ecological adaptation. In this study, we analysed the morphometric data of , a rare and endangered species, to examine sexual dimorphism in size and shape.

Firework Optimization Algorithm-Based Diagnosis of Hepatocellular Carcinoma and Hepatic Cavernous Hemangioma Using MRI Images.

This study was aimed to explore the diagnostic features of magnetic resonance imaging (MRI) on hepatocellular carcinoma (HCC) and hepatic cavernous hemangioma (HCH). A fireworks algorithm optimization (FAO) was proposed based on the fireworks algorithm (FA), and it was compared with the maximum between-class variance method (OTSU) and the maximum entropy threshold method (KSW) for analysis. In addition, it was applied to the diagnosis of MRI images of 55 HCC patients in the experimental group (group E) and 55 HCH patients in the control group (group C).

Impact of edaravone on serum CXC chemokine ligand-13 levels and perioperative neurocognitive disorders in elderly patients with hip replacement.

Background: Perioperative neurocognitive disorders (PND) are a series of severe complications in the perioperative and anesthetic periods with a decline in memory, execution ability, and information processing speed as the primary clinical manifestation. This study aimed to evaluate the impact of edaravone (EDA) on PND and peripheral blood C-X-C motif chemokine ligand 13 (CXCL13) levels in elderly patients with hip replacement.

Methods: A total of 160 elderly patients undergoing hip arthroplasty in Affiliated Dongguan People's Hospital of Southern Medical University (from March 2016 to March 2018) were randomly and double-blindly categorized into an EDA group and a control group (CON).