Effect of lateral wedge-shaped orthopedic insole on patients with genu varus: A protocol for systematic review and meta-analysis.

Background: Genu varus (GV) is a common deformity characterized by leg bending, which seriously threatens human health. At present, there is no definite conclusion to explain the cause of genu varus. The purpose of this study is to systematically review and meta-analysis the effectiveness and scientific basis of the clinical efficacy of customized orthopedic insoles on genu varus and hope to provide a reference for future research in this field.

Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.

Hepatitis B is a leading cause of death worldwide. Here, we performed a large, population-based, cross-sectional study in Chongqing, China from 2011 to 2016 to assess the prevalence of HBsAg among couples of reproductive age, to predict subsequent trends, and to provide evidence for the WHO goal of "the elimination of viral hepatitis as a public health threat by 2030". A total of 386,286 couples aged 20 to 49 years were enrolled in the study.

The relationship between urban and rural health insurance and the self-rated health of migrant workers in Southwest China.

Background: Following health insurance reforms, China's health care system has made great progress. However, there are still huge differences between the urban and rural health insurance systems. For rural-to-urban migrant workers, there may be differences in the use of urban and rural health insurance to improve their health status.

Association between obesity status and successful aging among older people in China: evidence from CHARLS.

Background: The paper aimed to examine the association between obesity status and successful aging among elderly adults in China and further find gender differences in the effect of components of successful aging on obesity status.

Methods: The data came from the follow-up survey(2015) of China Health and Retirement Longitudinal Study (CHARLS) and 4019 dwellers age 60 and over are included. Obesity status were defined by the body mass index (BMI) according to Chinese criteria.

Obesity and the onset of depressive symptoms among middle-aged and older adults in China: evidence from the CHARLS.

Background: The association between obesity and depression has been documented in previous systematic studies but remains controversial. Many prospective studies have focused on children and youth, and several studies have examined this relationship among older populations. This study of the changes in obesity status aimed to examine the association between depression and obesity among middle-aged and elderly adults in China.

Identification of pyruvate dehydrogenase kinase 1 inhibitors with anti-osteosarcoma activity.

Overexpression of pyruvate dehydrogenase kinases (PDKs), especially PDK1 has been observed in a variety of cancers. Thus, targeting PDK1 offers an attractive opportunity for the development of cancer therapies. In this letter, we reported the identification of two novel PDK1 inhibitors as anti-osteosarcoma agents.

[Sleep Duration and Abdominal Obesity in Elderly in China].

Objective: To determine the relationship between sleep duration and abdominal obesity in elderly in china.

Methods: Data were drawn from the 2013 China Health and Retirement National Investigation (China Health and Retirement Longitudinal Study, CHARLS). The prevalence of abdominal obesity in the elderly who had a normal range of sleep duration was compared with those who had a shorter or longer sleep duration using Chi-square tests and binary logistic regression models.

[Perceptions and Attitudes of Chengdu Residents toward "Medical and Aged Care" Integrated Models].

Objectives: To investigate the perceptions and attitudes of Chengdu residents toward "medical and aged care" integrated models and associated factors.

Methods: A cross-sectional questionnaire survey was conducted in 935 residents who were 45 years or older in 8 communities in Chengdu. Descriptive analyses and logistic binary regression analyses were performed.

[Prevalence and Associated Factors of Arthritis in Middle- and Old-aged Populations in China].

Objectives: To determine the prevalence of arthritis in middle- and old-aged populations in China and associated factors.

Methods: Data were drawn from the 2013 China Health and Retirement Longitudinal Study (CHARLS). Binary logistic regression analyses were performed to examine the associations of arthritis with social economic status (age, gender, areas, education), comorbidity (hypertension, dyslipidaemia, diabetes, cancer, chronic lung disease, liver disease, heart disease, stroke, kidney disease, digestive disease, asthma), lifestyle (smoking, drinking, sleeping) and mental health (depression symptoms).

[Urban-Rural Differences in the Role of Family Support in Physical and Mental Health of Elderly People in China].

Objectives: To investigate social support for elderly in urban and rural settings, and determine its role in physical and psychological health of the elderly populations.

Methods: Data were extracted from the 2013 China Health and Retirement Longitudinal Study (CHARLS). Physical health was measured by the ADL/IADL scale.

[Depressive Symptoms in the Mid- and Old-aged People in China].

Objectives: To determine the prevalence and determinants of depressive symptoms in the mid- and old-aged people in China.

Methods: Data were extracted from the 2013 China Health and Retirement Longitudinal Study (CHARLS),which containthe Center Epidemiologic Studies-Depression scale(CES-D). Binary logistic regression models were developed to identify factors associated with the prevalence of depression symptoms.

[Regional Differences and Determinants of Self-rated Health in Elderly].

Objective: To determine differences of self-rated health in elderly people across geographic regions of China, and to identify factors influencing self-rated health of elderly.

Methods: Ordered logistic modeling was performed using the China Health and Retirement Longitudinal Study (CHARLS) data in 2013.

Results: Elderly people resided in Eastern China had better self-rated health than their counterparts residing in Middle (partial regression coefficient 0.