Bioinspired Core-shell nanospheres integrated in multi-signal immunochromatographic sensor for high throughput sensitive detection of Bongkrekic acid in food.

Nowadays, notable progress has been achieved in detecting foodborne toxins by employing nanoenzyme-based lateral flow immunoassay (NLFIA) sensors in point-of-care testing (POCT). It continues to be a major challenge to maximize the enzyme-like performance of nanozymes for educe any potential uncertainties in catalytic process. In this study, we employed a facile and efficient self-assembly approach to fabricate nucleoid-shell structured biomimetic nanospheres CuS@Au-Pt (CAP), which demonstrates enhanced brightness of the colorimetric signal, excellent affinity, and excellent peroxidase activity.

Trifunctional Nanocomposites with Colorimetric Magnetic Catalytic Activities Labels in Sandwich Immunochromatographic Detection of O157:H7.

The emergence of nanoenzymes has catalyzed the robust advancement of the lateral flow immunoassay (LFIA) in recent years. Among them, multifunctional nanocomposite enzymes with core-shell architectures are considered preferable for promoting the sensing ability due to their good biocompatibility, precise control over size, and surface properties etc. Herein, we developed a dual-channel ensured lateral flow immunoassay (DFLIA) platform utilizing a magnetic, colorimetric, and catalytic multifunctional nanocomposite enzyme (FeO@TCPP@Pd) [TCPP, Tetrakis (4-carboxyphenyl) porphyrin] for the ultrasensitive and highly accurate rapid detection of O157:H7 ( O157:H7).