Publications by authors named "Huiqi Li"

Introduction: We investigated whether living in immigrant-dominated neighbourhoods constituted a risk factor for COVID-19 infection and hospitalisation among healthcare workers (HCWs) in Sweden, and if so, whether such exposure exacerbated the risk of COVID-19 among immigrant HCWs.

Methods: We used population-based register data from HCWs aged 20-62 years (N=86 187) resident in 14 Swedish municipalities (3 of which are Sweden's largest metropolitan cities) on 1 January 2020. Residential neighbourhoods of the HCWs were categorised into three groups: Swedish-dominated, mixed and immigrant-dominated.

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: All-cause mortality consisting of several heterogeneous subgroups does not have a well-defined set of risk factors. Despite the well-described role of oral hygiene on mortality, the association between the condition of the existing dentition and mortality remains unclear. Therefore, we embarked on the current study to assess the association of oral hygiene self-care (OHS) with all-cause mortality.

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Conflicts between humans and animals in agricultural and settlement areas have recently increased, resulting in significant resource loss and risks to human and animal lives. This growing issue presents a global challenge. This paper addresses the detection and identification of offending animals, particularly in obscured or blurry nighttime images.

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The goal of this work is to investigate the sociodemographic characteristics and health status of women with breast cancer (BC) in association with COVID-19 by menopausal status. In a Swedish register-based cross-sectional study, we compared women with BC and with or without a positive COVID-19 test, stratified by menopausal status (age ≥ 51 years). Socioeconomic characteristics and health status (represented by diagnoses registered in 5 years- and prescription dispensed in 2 years preceding Jan 2020) were considered in association with COVID-19 diagnosis.

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Background: Remote patient monitoring (RPM) has been evaluated in COPD, but with varying results. We aimed to evaluate whether a tablet system that monitors disease-related parameters in patients with COPD could influence physical and mental health-related quality of life, compared with usual care (UC).

Methods: 70 patients with Global Initiative for Chronic Obstructive Lung Disease (GOLD) group D COPD (61% women, aged 71±8 years, forced expiratory volume in 1 s % predicted 41±13%, COPD Assessment Test (CAT) 19±7 points) were recruited at the COPD centre in Gothenburg, Sweden, and randomised to a tablet-based RPM system or UC for a 26-week period, after which they crossed over to the alternative management for another 26 weeks.

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  • The thickness of retinal layers is linked to eye diseases like glaucoma and optic disc drusen, making accurate segmentation crucial for diagnosis and treatment.
  • Optical coherence tomography (OCT) is a key technology used to visualize these retinal structures, but current methods lack consistent segmentation performance across different datasets with varying conditions.
  • The proposed segmentation method enhances boundary definition and model sensitivity to retinal structures while addressing data imbalance, achieving top performance on multiple datasets.
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Hydrogen sulfide (HS) is a pervasive environmental and industrial pollutant that poses a substantial threat to human health. Even short-term exposure to HS can result in severe respiratory and neurological damage. However, the underlying mechanisms of its biotoxicity remain unclear.

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Demyelinating diseases including multiple sclerosis are associated with prior infectious exposures, so we assessed whether SARS-CoV-2 infection is associated with subsequent diagnoses of non-multiple sclerosis demyelinating diseases and multiple sclerosis. All residents of Sweden aged 3-100 years were followed between 1 January 2020 and 30 November 2022, excluding those with demyelinating disease prior to 2020, comprising 9 959 818 individuals divided into uninfected and those who were infected were categorized into those with and without hospital admission for the infection as a marker of infection severity. Cox regression assessed the risk of two separate outcomes: hospital diagnosed non-multiple sclerosis demyelinating diseases of the CNS and multiple sclerosis.

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  • Whispering gallery mode (WGM) resonators are popular in integrated photonics for their efficient microlaser properties, thanks to their high quality factor, compact size, and small mode volume.
  • A Nd:GGG crystal was transformed into a thin film using an ion implantation-enhanced etching technique, and then shaped into a 20 μm microdisk using focused ion beam technology.
  • The microdisk's placement impacted its heat dissipation and laser performance, showing different laser thresholds (32 μW on a holder and 17 μW on a wafer) and varying mode shifts in response to the thermal conditions during operation.
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  • The study investigates the side effects of COVID-19 vaccinations and infections, focusing on the benefits of self-reporting symptoms through a digital system called Symptoms.
  • Researchers aimed to understand how this system can capture patient-reported outcomes, which vary in importance depending on individual needs.
  • A total of 731 participants used the Symptoms system to track their health-related quality of life and symptoms, highlighting the relevance of personal experiences in monitoring vaccine side effects.
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  • * These pollutants cause oxidative damage and can disrupt the reproductive systems of fish, which are vital for both ecological balance and human food sources.
  • * The review focuses on the specific reproductive effects of these plastics on fish, covering topics like fecundity, offspring quality, and developmental changes at the molecular level, highlighting their significance in environmental toxicology.
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During the coronavirus disease 2019 (COVID-19) pandemic, Sweden emphasized voluntary guidelines over mandates. We exploited a rapid change and reversal of the Public Health Agency of Sweden's COVID-19 testing guidelines for vaccinated and recently infected individuals as a quasi-experiment to examine sociodemographic differences in the response to changes in pandemic guidelines. We analyzed daily polymerase chain reaction tests from 1 October 2021 to 15 December 2021, for vaccinated or recently infected adults (≥20 years; n = 1 596 321) from three Swedish regions (Stockholm, Örebro, and Dalarna).

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  • The study explored the connection between sleep duration during midlife and the development of depressive symptoms in late life among 14,361 participants in the Singapore Chinese Health Study.
  • It found that sleeping 5 hours or less during midlife increased the risk of depression in later years, while longer sleep (9 hours or more) did not show a significant link at that time.
  • In late life, both insufficient and excessive sleep were associated with depressive symptoms, indicating that sleep duration issues remain relevant throughout aging.
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  • The study investigates the cardiovascular effects of COVID-19 mRNA vaccination in over 8 million Swedish adults, focusing on risks for myocarditis, pericarditis, dysrhythmias, heart failure, myocardial infarction, and cerebrovascular events.
  • Results indicate that while there is a temporary increase in risks for myocarditis and extrasystoles shortly after vaccination, overall cardiovascular risks significantly decrease after full vaccination, particularly after the third dose.
  • The findings highlight the importance of vaccination in reducing severe cardiovascular complications associated with COVID-19, validating its protective benefits despite some rare adverse events.
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Background: China has the largest number of dementia patients worldwide. The prolonged course of dementia has a serious negative impact on the economy and quality of life of patients and their families.

Objective: The purpose of this study was to conduct a systematic review and meta-analysis of the existing literature about economic burden and quality of life of people with dementia in China.

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  • - Individuals with mental illness are at a higher risk for severe COVID-19 outcomes, but studies on their vaccination uptake have shown mixed results.
  • - This research analyzed data from multiple cohort studies and Swedish registers to explore the relationship between mental illness and COVID-19 vaccination rates.
  • - Findings revealed that while overall vaccine uptake was high in both groups, there was a slight decrease in vaccination rates among unmedicated individuals with mental illness, indicating a need for further investigation into this subgroup.
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  • The study examined how vegetable and fruit intake during midlife affects the chances of experiencing physical frailty later in life among Chinese adults in Singapore, using a prospective cohort design over 20 years.
  • Results showed that higher vegetable consumption was linked to lower odds of frailty, particularly in areas like weakness measured by handgrip strength, while fruit intake did not show a significant impact.
  • Further analysis indicated that the association between vegetable intake and reduced frailty diminished when accounting for specific nutrients like β-carotene and folate, suggesting these nutrients might play a crucial role in the observed effects.
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  • Transition metal nitride-based materials are gaining attention as effective alternatives to precious metals for catalyzing the oxygen reduction reaction in alkaline environments.
  • The study highlights how the structure of a manganese nitride core influences the growth of a manganese oxide shell, resulting in significantly improved electrocatalytic activity.
  • Findings suggest that the enhanced performance is due to a more reactive hydroxylated surface on the manganese oxide, shaped by the strain from the underlying nitride, paving the way for future advancements in catalyst design.
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Due to their robust migration capabilities, slow degradation, and propensity for adsorbing environmental pollutants, micro(nano)plastics (MNPs) are pervasive across diverse ecosystems. They infiltrate various organisms within different food chains through multiple pathways including inhalation and dermal contact, and pose a significant environmental challenge in the 21st century. Research indicates that MNPs pose health threats to a broad range of organisms, including humans.

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  • The cytochrome P450 (CYP) gene superfamily is crucial for various physiological processes, but its specific roles in gonad development of the Pacific oyster (Crassostrea gigas) are largely unknown.
  • This study identified 116 CgCYP genes and analyzed their expression patterns, revealing significant variations in molecular weights and amino acid lengths, as well as 26 cis-acting elements associated with these genes.
  • Over-expression of 69 CgCYP genes during early gonad development suggests their importance, especially those like CgCYP1 and CgCYP15, which show higher expression in female gonads, indicating a key role in female reproductive development.
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  • Assessing COVID-19 risk in asthma patients is complex because the impact of risk factors varies significantly among different age groups, which can lead to misleading insights if studied together.
  • The study examined 201,140 asthma patients from the Swedish National Airway Register, analyzing COVID-19 outcomes like infection rates, hospitalization, and mortality from January 2020 to February 2021, with specific attention to age-related factors.
  • Results showed distinct differences in risk factors for COVID-19 hospitalizations and deaths across age groups, highlighting the importance of asthma control, lung function, and other health conditions, with serious outcomes primarily occurring in patients aged 40 and older.
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The utilization of deformed microcavities, such as elliptical microdisks, has been widely acknowledged as an effective solution for achieving free-space emission in microcavity lasers. However, the deformations introduced in the microcavity structure tend to decrease the quality factor (Q factor), resulting in weakened output intensity. To address this issue, one potential approach is to employ highly efficient laser gain media that can compensate for the negative impact of the structure on the output intensity.

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Background: It is unclear if improving diet quality after midlife could reduce the risk of physical frailty at late life. We aimed to associate changes in diet quality after midlife with physical frailty at late life.

Methods: Diet quality in 12,580 participants from the Singapore Chinese Health Study was assessed with the Dietary Approaches to Stop Hypertension (DASH) scores at baseline (1993-1998; mean age 53 years) and follow-up 3 (2014-2016; mean age 73 years).

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  • A study investigated the link between fruit and vegetable intake in midlife and the risk of depressive symptoms later in life in a cohort of Chinese adults living in Singapore, involving 13,738 participants.
  • Researchers found that higher fruit consumption was associated with a lower likelihood of depressive symptoms, particularly with fruits like oranges and bananas, suggesting a dose-response relationship.
  • Conversely, vegetable intake did not show a significant effect on depressive symptoms, leading to recommendations for increased fruit consumption to potentially improve mental health outcomes in older age.
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Preclinical and limited epidemiological studies suggest that oxidative stress may be implicated in geriatric depression. Our study investigated the association between midlife dietary total antioxidant capacity (TAC) and depressive symptoms in late life among 13,712 participants in a population-based cohort of Chinese in Singapore. At baseline (1993-1998), intake of antioxidants from diet and supplements at a mean age of 52.

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