Publications by authors named "Huimei Guo"

Article Synopsis
  • * Out of 84 patients studied, 76.2% were found frail using at least one tool, but there was low overall consistency among all four tools, while IMWG-FI and MRP showed moderate agreement.
  • * Significant differences in survival rates were observed between frail and non-frail groups based on some tools, but not across all frailty tools, suggesting that combining IMWG-FI and MRP may enhance the accuracy of frailty assessments.
View Article and Find Full Text PDF
Article Synopsis
  • * A clinical case is presented involving a 50-year-old woman with MM who experienced acute kidney injury over 20 days after auto-HSCT and was later diagnosed with retroperitoneal fibrosis (RPF).
  • * The patient's kidney obstruction was successfully treated with a transurethral vesicoureteral stent, restoring her renal function; the case highlights the rare occurrence of RPF post-MM transplantation and suggests the need for further investigation into the link between the two conditions.
View Article and Find Full Text PDF

Objective: To investigate a reliable clinical indication for predicting the therapeutic response of decitabine therapy in the patients with myelodysplastic syndromes (MDS).

Methods: The clinical efficacy of decitabine for 55 cases of MDS was analyzed retrospectively. According to the lymphocyte level at d28 after the first time treatment with decitabine, the patients were divided into high lymphocyte level group (H-Lym≥1.

View Article and Find Full Text PDF

Angiogenesis plays a significant role in the pathogenesis of multiple myeloma (MM). Microvesicles (MVs), a type of extracellular vesicles, are known as important players in cell-to-cell communication. MM-derived MVs have exhibited the activity of promoting angiogenesis.

View Article and Find Full Text PDF

Although red cell distribution width (RDW) and P-wave dispersion (Pwd) are strong independent predictors of atrial tachyarrhythmia (ATa), the association between these two factors in the occurrence of ATA has hitherto not been reported. We retrospectively analyzed the cases of ATa patients who underwent Holter monitoring at our hospital from October 2013 to August 2014. Clinical data including RDW and color doppler ultrasonography data were collected, and Pwd was calculated from synchronous recording of P-wave intervals of 12-lead electrocardiograms.

View Article and Find Full Text PDF

To investigate the relationship between red blood cell distribution width (RDW) and diurnal corrected QT (QTc) variation in patients with coronary heart disease. This retrospective study included 203 patients who underwent coronary angiography between February 2013 and June 2014. RDW values and dynamic electrocardiography (Holter) results were collected to investigate the relationship between RDW and diurnal QTc variation.

View Article and Find Full Text PDF

The aim of this study was to investigate the effects of miR-155 inhibitor transfection on the proliferation and apoptosis of THP-1 cells. The miR-155 inhibitor was transfected into THP-1 cells (THP-1I) by using X-treme GENE siRNA transfection reagent. Cells without transfection (THP-1C) and cells with negative transfection (THP-1IC) were used as controls.

View Article and Find Full Text PDF