Association between all-cause mortality and triglyceride glucose body mass index among critically ill patients with sepsis: a retrospective cohort investigation.

Background: We determined utilizing a sepsis participant cohort whether there is a significant association between TyG-BMI (triglyceride glucose body mass index) and mortality rates at any stage.

Methods: Herein, a historical cohort investigation approach was adopted, using information provided by the Medical Information Mart for Intensive Care-IV (MIMIC-IV). We categorized the included individuals in accordance with their TyG-BMI data quartiles, and the primary outcomes were mortality during the hospital stay and death rate due to any reason at postadmission day 28, 90, and 365.

Learning implementation of a guideline based decision support system to improve hypertension treatment in primary care in China: pragmatic cluster randomised controlled trial.

Objective: To evaluate the effectiveness of a clinical decision support system (CDSS) in improving the use of guideline accordant antihypertensive treatment in primary care settings in China.

Design: Pragmatic, open label, cluster randomised trial.

Setting: 94 primary care practices in four urban regions of China between August 2019 and July 2022: Luoyang (central China), Jining (east China), and Shenzhen (south China, including two regions).

Damage Model of Steel Fiber-Reinforced Coal Gangue Concrete under Freeze-Thaw Cycles Based on Weibull Distribution.

In order to improve the utilization rate of coal gangue and expand the application range of coal gangue concrete (CGC), a certain proportion of steel fiber was added to the concrete, and the freeze-thaw cycles (FTCs) and flexural tests were used to explore the effects of different mass replacement rates of coal gangue (0%, 25%, 50%, 75%, and 100%) and different proportions of the volumetric blending of the steel fiber (0%, 0.8%, 1.0%, and 1.

Experimental study on remediation of petroleum-contaminated soil by combination of freeze-thaw and electro-osmosis.

Electro-osmosis has been well recognized as a technique for the remediation of petroleum-contaminated soil, however seasonally freezing and thawing adds the complexity of petroleum mobility in cold regions. To investigate the influence of freeze-thaw on the electroosmotic removal of petroleum and explore the enhancement of freeze-thaw on the electroosmotic remediation efficiency in remediating the petroleum-contaminated soils, a set of laboratory tests were performed in three types of treatment modes, freeze-thaw (FT), electro-osmosis (EO) and freeze-thaw combined electro-osmosis (FE). The petroleum redistributions as well as the moisture content changes after the treatments were evaluated and compared.

Anchoring grassland sustainability with a nature-based small burrowing mammal control strategy.

Over the last 40 years, a burrowing mammal eradication policy has been prevalent on the Qinghai-Tibetan Plateau (QTP). This policy is based on similar burrowing mammal eradication programs in other areas and is justified on the assumptions that burrowing mammals compete with livestock for forage and contribute to grassland degradation. However, there is no clear theoretical or experimental evidence supporting these assumptions.

Formation processes of shallow ground ice in permafrost in the Northeastern Qinghai-Tibet Plateau: A stable isotope perspective.

The Source Area of the Yellow River (SAYR) on the Northeastern Qinghai-Tibet Plateau (QTP) stores substantial amounts of ground ice, which plays a significant role in understanding the hydrological processes and past permafrost evolution on the QTP. However, little is known about the initial sources and controlling factors of the ground ice in the SAYR. In this study, for the first time, ground ice stable isotope data (δO, δD, and d-excess) are presented, along with cryostratigraphic information for nine sites is integrated into three cryostratigraphic units (palsa, thermo-gully, and lake-affected sites) in the central SAYR.

Determination of methanol partition coefficient in octanol/water system by a three-phase ratio variation headspace gas chromatographic method.

Determining the methanol partition coefficient (K) in octanol/water system is important to assess the risk of its impact to humans and the environment. In this paper, we report a novel method for the determination of the K of methanol with headspace gas chromatography (HS-GC), using a three-phase equilibrium-based phase ratio variation approach. Three headspace vials with different phase ratios [(1) 0.

Holocene monsoon dynamics at Kunlun Pass on the northeastern Qinghai-Tibet Plateau.

Various proxy records have been used for the understanding of environmental and climate variations during the Holocene. Here, for the first time, we use meteoric Be isotope measurements performed on sediments from a drill core collected at the Kunlun Pass (KP) on the northeastern Qinghai-Tibet Plateau (NETP) to investigate hydroclimate changes during the Holocene. The Be flux suggests relative low levels in the Early Holocene, followed by a sharp increase to high values at around 4 ka BP (4 ka BP = 4000 years before present).

Permafrost Degradation Leads to Biomass and Species Richness Decreases on the Northeastern Qinghai-Tibet Plateau.

Degradation of permafrost with a thin overlying active layer can greatly affect vegetation via changes in the soil water and nutrient regimes within the active layer, while little is known about the presence or absence of such effects in areas with a deep active layer. Here, we selected the northeastern Qinghai-Tibet Plateau as the study area. We examined the vegetation communities and biomass along an active layer thickness (ALT) gradient from 0.

Use of Be isotope to predict landscape development in the source area of the Yellow River (SAYR), northeastern Qinghai-Tibet Plateau.

The magnitude of soil and sediment erosion and accumulation processes can profoundly affect landscape development and hamper efficient management of natural resources. Consequently, estimating the rates and causes of these processes is essential, particularly in remote regions, for prediction of changes in landform and river evolution and protection of local ecosystem. We here present the results of a soil and sediment erosion investigation in the Source Area of the Yellow River (SAYR), northeast Qinghai-Tibet Plateau based on a combined analysis of Be cosmogenic isotope and Soil and Water Assessment Tool (SWAT) simulation modelling.

Three-dimensional distribution of permafrost and responses to increasing air temperatures in the head waters of the Yellow River in High Asia.

Fine-scale three-dimensional (3D) permafrost distributions at the basin scale are currently lacking. They are needed to monitor climate and ecosystem change and for the maintenance of infrastructure in cold regions. This paper determined the horizontal and vertical distributions of permafrost and its quantitative responses to climate warming in the High Asia region by constructing a quasi-3D model that couples heat transfer and water movement and is forced by spatially-interpolated air temperatures using an elevation-dependent regression method.

Evaluation of groundwater discharge into surface water by using Radon-222 in the Source Area of the Yellow River, Qinghai-Tibet Plateau.

Understanding hydrological processes in the Source Area of the Yellow River (SAYR), Qinghai-Tibet Plateau, is vital for protection and management of groundwater and surface water resources in the region. In situ water measurements of exchange rates between surface water and groundwater are, however, hard to conduct because of the harsh natural conditions of the SAYR. We here present an indirect method using in situ Rn measurements to estimate groundwater discharge into rivers and lakes in the SAYR.

Thermal regime of warm-dry permafrost in relation to ground surface temperature in the Source Areas of the Yangtze and Yellow rivers on the Qinghai-Tibet Plateau, SW China.

Ecology, hydrology, and natural resources in the source areas of the Yangtze and Yellow rivers (SAYYR) are closely linked to interactions between climate and permafrost. However, a comprehensive study of the interactions is currently hampered by sparsely- and unevenly-distributed monitoring sites and limited field investigations. In this study, the thermal regime of warm-dry permafrost in the SAYYR was systematically analyzed based on extensive data collected during 2010-2016 of air temperature (T), ground surface temperature (GST) and ground temperature across a range of areas with contrasting land-surface characteristics.

Unraveling of permafrost hydrological variabilities on Central Qinghai-Tibet Plateau using stable isotopic technique.

Permafrost degradation on the Qinghai-Tibet Plateau (QTP) will substantially alter the surface runoff discharge and generation, which changes the recharge processes and influences the hydrological cycle on the QTP. Hydrological connections between different water bodies and the influence of thawing permafrost (ground ice) are not well understood on the QTP. This study applied water stable isotopic method to investigate the permafrost hydrological variabilities in Beiluhe Basin (BLB) on Central QTP.

No protection of permafrost due to desertification on the Qinghai-Tibet Plateau.

Desertification of tundra regions may form an escalating cycle with permafrost degradation where more permafrost thaw leads to continued desertification. This traditional viewpoint has been challenged in recent reports that state desertification protects the underlying permafrost. However, our measurements of soil temperature from nine sites in the Honglianghe River Basin, interior Qinghai-Tibet Plateau, show that desertification can degrade permafrost.

Hydrocarbon degraders establish at the costs of microbial richness, abundance and keystone taxa after crude oil contamination in permafrost environments.

Oil spills from pipeline ruptures are a major source of terrestrial petroleum pollution in cold regions. However, our knowledge of the bacterial response to crude oil contamination in cold regions remains to be further expanded, especially in terms of community shifts and potential development of hydrocarbon degraders. In this study we investigated changes of microbial diversity, population size and keystone taxa in permafrost soils at four different sites along the China-Russia crude oil pipeline prior to and after perturbation with crude oil.

Midline submental intubation might be the preferred alternative to oral and nasal intubation in elective oral and craniomaxillofacial surgery when indicated.

Purpose: No consensus exists to date regarding the best method of controlling the airway for oral or craniomaxillofacial surgery when orotracheal and nasotracheal intubations are unsuccessful or contraindicated. The most commonly used method of tracheostomy has been associated with a high degree of morbidity. Therefore, the present study was conducted to determine the indications, safety, efficacy, time required, drawbacks, complications, and costs of the midline submental intubation (SMI) approach in elective oral and craniomaxillofacial surgical procedures.

Topical review: the enigma of fibromyalgia.

Fibromyalgia is a syndrome characterized by chronic widespread pain, stiffness, nonrestorative sleep, fatigue, and comorbid conditions. Recognition of the condition and its associated medications and challenges, along with knowledge of treatment modifications and precautions in drug prescription, can ensure safe and effective delivery of oral health care in fibromyalgia patients. The ever-evolving research into the condition makes it necessary for the oral health care provider to be informed about the current state of the literature and treatment standards regarding the management of fibromyalgia patients.

Crude oil treatment leads to shift of bacterial communities in soils from the deep active layer and upper permafrost along the China-Russia Crude Oil Pipeline route.

The buried China-Russia Crude Oil Pipeline (CRCOP) across the permafrost-associated cold ecosystem in northeastern China carries a risk of contamination to the deep active layers and upper permafrost in case of accidental rupture of the embedded pipeline or migration of oil spills. As many soil microbes are capable of degrading petroleum, knowledge about the intrinsic degraders and the microbial dynamics in the deep subsurface could extend our understanding of the application of in-situ bioremediation. In this study, an experiment was conducted to investigate the bacterial communities in response to simulated contamination to deep soil samples by using 454 pyrosequencing amplicons.

A new headspace gas chromatographic method for the determination of methanol content in paper materials used for food and drink packaging.

This study reports on a method for determination of methanol in paper products by headspace gas chromatography (HS-GC). The method is based on the hydrolysis of the pulp or paper matrix, using a phosphoric acid solution (42.5%) as the medium at 120 °C in 5 h (excluding air contact) in order to release matrix-entrapped methanol, which is then determined by HS-GC.

[Adenovirus-mediated canine interferon-gamma expression and its antiviral activity against canine parvovirus].

Objective: To construct recombinant adenovirus containing canine interferon-gamma (cIFN-gamma) gene and to investigate its antiviral activity against canine parvovirus in Madin-Darby canine kidney cells (MDCK). [Methods] The cIFN-gamma gene was inserted into adenovirus shuttle plasmid to construct pShuttle3-cIFN-gamma expression vector, from which the cIFN-gamma expression cassette was transferred into the adenovirus genomic plasmid pAdeno-X by specific restriction sites to generate recombinant adenovirus genomic plasmid pAd-cIFN-gamma. The pAd-cIFN-gamma plasmid was linearized by digestion and transfected into human embryonic kidney (HEK) 293T cells to generate the replication-defective cIFN-gamma recombinant adenovirus (Ad-cIFN-gamma).

Pyrosequencing investigation into the bacterial community in permafrost soils along the China-Russia Crude Oil Pipeline (CRCOP).

The China-Russia Crude Oil Pipeline (CRCOP) goes through 441 km permafrost soils in northeastern China. The bioremediation in case of oil spills is a major concern. So far, little is known about the indigenous bacteria inhabiting in the permafrost soils along the pipeline.

[Change of T lymphocyte subsets, interleukin-2 and tumor necrosis factor-alpha in tumor-bearing mice and patients with oral cancer receiving thermo-chemotherapy].

Objective: To investigate the change of T lymphocyte subsets, interleukin (IL)-2 and tumor necrosis factor (TNF)-alpha in the tumor- bearing mice and patients with oral cancer receiving thermo-chemotherapy, and investigate the correlation among them.

Methods: After treatments, the expression of lymphocyte transformation index (LTI), IL-2 and TNF-alpha in the tumor-bearing mice were detected with methyl thiazolyl tetrazolium (MTT), the expression of IL-2 and TNF-alpha in the patients with oral cancer were detected with MTT, the expression of LTI, CD4+ and CD8+ were detected with 3H-TdR incorporation.

Results: LTI, IL-2 and TNF-alpha of thermo-chemotherapy group (HP group) had no significant difference comparing with those of normal mice group (N group) (P>0.