Publications by authors named "Huijie Yue"
Article Synopsis
- There are differences in bioactivity among various forms of vitamin K (VK), which impact anticoagulation therapy.
- A study established a method to measure levels of VK1 and two forms of VK2 (MK-4 and MK-7) in plasma samples from cardiovascular patients.
- Results showed that concentrations of MK-7 and total VKs were significantly associated with initial anticoagulation levels (INR0), suggesting these vitamin K forms should be considered when adjusting anticoagulation doses.
Rapid and accurate detection of pathogens and antimicrobial-resistant (AMR) genes of the pathogens are crucial for the clinical diagnosis and effective treatment of infectious diseases. However, the time-consuming steps of conventional culture-based methods inhibit the precise and early application of anti-infection therapy. For the prompt treatment of pathogen-infected patients, we have proposed a novel tube array strategy based on our previously reported FARPA (FEN1-aided recombinase polymerase amplification) principle for the ultra-fast detection of antibiotic-resistant pathogens on site.
View Article and Find Full Text PDFAntimicrobial susceptibility testing (AST) is an effective way to guide antibiotic selection. However, conventional culture-based phenotypic AST is time-consuming. The key point to shorten the test is to quantify the small change in the bacterial number after the antibiotic exposure.
View Article and Find Full Text PDFPurpose: The emergence of ceftazidime-avibactam (CZA) resistance in carbapenem-resistant Klebsiella pneumoniae (CRKP) has been increasingly reported in recent years. We aimed to identify the risk factors of CZA-resistant CRKP infection and assess clinical outcomes of the patients.
Methods: The study retrospectively analyzed the clinical and microbiological data of patients with CRKP infection to identify risk factors, clinical features, and outcomes using multivariate logistic regression analysis.