Background: Few studies have explored the effects of arsenic exposure on depressive symptoms and the underlying mechanisms of its influence on this relationship. This study aimed to assess the impact of urinary arsenic on depressive symptoms and the mediating and moderating roles of folate and dietary inflammation index (DII).
Methods: Cross-sectional data from 9775 participants (≥20 years) in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2020 were used for analysis.
Huan Jing Ke Xue
October 2024
Ecotoxicol Environ Saf
October 2024
Background: Mold exposure is a common environmental issue that can adversely affect health, particularly among older adults. The impact of mold exposure on anxiety symptoms in this population has not been extensively studied.
Objective: This study aims to examine the relationship between mold exposure and anxiety symptoms in older adults, considering the mediating role of cognitive function and the moderating effects of open window ventilation and multivitamin supplementation.
With the rapid urbanization and aging population, depression has become a severe public health issue globally, affecting millions of individuals and significantly impacting their quality of life and healthcare costs. Urban resilience refers to a city's ability to absorb, recover, and prepare for future shocks, ensuring sustainable development despite challenges. This study aims to explore the impact of urban resilience on depressive symptoms among middle-aged and elderly adults.
View Article and Find Full Text PDFAlzheimer's disease (AD) is an irreversible brain disorder, which has been found to be associated with neurotoxic amyloid-β oligomers (AβO). The early diagnosis of AD is still a great challenge. Herein, inspired by the hierarchical channel structure of natural wood, we design and demonstrate a low-cost and sensitive wood channel-based fluidic membrane for electrochemical sensing of AβO.
View Article and Find Full Text PDFEnantioselective identification of chiral molecules is regarded as one of the key issues in biological and medical sciences because of their configuration-dependent effects on biological systems. In this study, we developed an electrochemical platform based on a tandem recognition-reaction zone design in TiO nanochannels for the specific recognition of reducing enantiomers. In this system, MIL-125(Ti) Ti-metal-organic frameworks, grown in TiO nanochannels, provided a homochiral recognition environment postmodification with l-tartaric acid (l-TA); MnO nanosheets possessing both glucose oxidase (GOD)- and peroxidase (POD)-mimicking activities served as the target-reactive zone at the end of the nanochannels.
View Article and Find Full Text PDFMetal-organic frameworks (MOFs) demonstrate strong potential in biosample separation. However, the obtained MOFs powders are unsuitable for recovery techniques in an aqueous solution, especially the challenges of withdrawing MOFs particles and expanding their functions for specific applications. Herein, a general strategy is designed utilizing metal oxide-nanochannel arrays as precursors and templates for in-situ selective growth of MOFs structures.
View Article and Find Full Text PDFEnantioselective identification of chiral molecules is of paramount importance in medical science, biochemistry, and pharmaceutics owing to the configuration-dependent activities of enantiomers. However, the identical physicochemical properties of enantiomers remain challenging in chiral sensing. In this study, inspired by the peroxidase-mimicking activity of Fe(III)-based nanomaterials, an enantioselective artificial architecture is constructed on TiO nanochannels.
View Article and Find Full Text PDFMonosaccharides play significant roles in daily metabolism in living organisms. Although various devices have been constructed for monosaccharide identification, most rely on the specificity of the natural enzyme. Herein, inspired by natural ionic channels, an asymmetrical MOF-in-nanochannel architecture is developed to discriminate monosaccharide enantiomers based on cascade reactions by combining oxidase-mimicking and Fenton-like catalysis in homochiral mesoporous CuMOF pockets.
View Article and Find Full Text PDFAs an intriguing and intrinsic feature of life, chirality is highly associated with many significant biological processes. Simultaneous recognition and quantification of enantiomers remains a major challenge. Here, a sensitive enantiomer identification device is developed on TiO nanochannels the design of cascade recognition-quantification zones along the nanochannels.
View Article and Find Full Text PDFStudy Objectives: The goal of this study was to investigate the value of the long-term average spectrum in the acoustic analysis of snore sounds arising from different sources in the upper airway.
Methods: Long-term average spectrum was used to analyze sequences of 10 consecutive snore sounds that had been divided into 2 groups, soft-palate type and lateral-wall type, according to the vibration site generating the snore sounds and the patterns of soft tissue collapse in the upper airway as identified by drug-induced sleep endoscopy. We calculated the first spectral peak, mean spectral energy, high-frequency energy, 0-1 kHz spectral energy, 1-5 kHz spectral energy, and 0-1 kHz/1-5 kHz difference from each group and compared the differences between them.
As cancer nanotherapeutics, the ideal multifunctional nanoparticles not only have the processing ability to accumulate effectively in tumors, but also can be excreted rapidly from the body via renal clearance after effective treatment. Melanin is an endogenous biological material, and gelatin has natural biocompatibility and biodegradability. Such materials are more promising in the development of diagnostic and therapeutic nanoplatform for future clinical translation.
View Article and Find Full Text PDFEnrichment and separation of specific endogenous molecules are essential for disease diagnosis and the pharmaceutical industry. Although many solid sorbents have been developed for target molecule enrichment, simultaneous separation of multitargets is still a challenge for adsorbents. In this study, we develop a multitarget selective sorbent based on a nanochannel membrane prepared by the anodization of a Ti-Cu alloy.
View Article and Find Full Text PDFIn this paper, the sensor fault detection problem considering the drilling disturbances is studied for the dynamic point-the-bit rotary steerable system. Firstly, the DPRSS is modeled as a linear system with the drilling disturbances, including unknown inputs, measurement noises, and model perturbations. Then, a finite-frequency zonotopic fault detection observer is proposed.
View Article and Find Full Text PDFThe high cost and easy denaturation of natural enzymes under environmental conditions hinder their practical usefulness in sensing devices. In this study, peroxidase (POD)-like metal-organic frameworks (MOFs) were grown in the nanochannels of an anodized TiO membrane (TiONM) as an electrochemical platform for multitarget sensing. By directly using a nanochannel wall as the precursor of metal nodes, Ti-MOFs were derived on the nanochannel wall.
View Article and Find Full Text PDFBackground: Snoring source analysis is essential for an appropriate surgical decision for both simple snorers and obstructive sleep apnea/hypopnea syndrome (OSAHS) patients.
Objective: As snoring sounds carry significant information about tissue vibrations within the upper airway, a new feature entitled compressed histogram of oriented gradients (CHOG) is proposed to recognize vibration patterns of the snoring source acoustically by compressing histogram of oriented gradients (HOG) descriptors via the multilinear principal component analysis (MPCA) algorithm.
Methods: Each vibration pattern corresponds to a sole or combinatorial vibration among the four upper airway soft tissues of soft palate, lateral pharyngeal wall, tongue base, and epiglottis.
Au nanoparticles were asymmetrically fabricated at one tip of TiO2 nanochannels by combining a photocatalytic reaction and limited penetration of light. Using the asymmetrical nanochannel-based membrane as a plasma absorber, near-infrared-gated artificial ionic nanochannels were designed.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
November 2019
Among natural energy resources, methane clathrate has attracted tremendous attention because of its strong relevance to current energy and environment issues. Yet little is known about how the clathrate starts to nucleate and disintegrate at the molecular level, because such microscopic processes are difficult to probe experimentally. Using surface-specific sum-frequency vibrational spectroscopy, we have studied in situ the nucleation and disintegration of methane clathrate embryos at the methane-gas-water interface under high pressure and different temperatures.
View Article and Find Full Text PDFThe level of hydrogen sulfide in the brain and vasculature has long been associated with human health and diseases. Hence, simple and robust analytical tools allowing determination of hydrogen sulfide levels are highly desirable. In this work, a biomineralization-driven ion gate in TiO nanochannel arrays for HS sensing was designed and developed.
View Article and Find Full Text PDFThe advent of 'Big Data' and 'Deep Learning' offers both, a great challenge and a huge opportunity for personalised health-care. In machine learning-based biomedical data analysis, feature extraction is a key step for 'feeding' the subsequent classifiers. With increasing numbers of biomedical data, extracting features from these 'big' data is an intensive and time-consuming task.
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