Publications by authors named "Huijian Ma"
Background: The diagnosis of primary small intestinal lymphoma (PSIL) is difficult. This study aimed to evaluate the clinical, radiological and endoscopic characteristics of PSIL and provide clue for diagnosis.
Methods: A total of 30 patients diagnosed with PSIL who underwent double balloon endoscopy (DBE) in the First Affiliated Hospital of Zhejiang University were retrospectively analyzed.
Background: Biglycan (BGN) is a small leucine-rich proteoglycan that participates in the production of excess extracellular matrix (ECM) and is related to fibrosis in many organs. However, the role of BGN in liver fibrosis remains poorly understood. This study aimed to investigate the role and mechanism of BGN in liver fibrosis.
View Article and Find Full Text PDFMelanoma is an aggressive disease with rapid progression and fast relapse, representing one of the formidable challenges in clinic. Current systemic therapies for melanoma exhibit limited anticancer potential due to the lack of specificity and limited efficacy. Herein, we design a cationic polymer (SCP-HA-PAE) by conjugating skin/cell penetrating peptide (SCP) and hyaluronic acid (HA) to the amphipathic polymer (poly β-amino esters, PAE), then fabricate the nanocarriers (SHP) composed by SCP-HA-PAE for delivering siRNA to skin melanoma by transdermal application.
View Article and Find Full Text PDFArticle Synopsis
- Skin serves as the body's primary barrier but is often damaged by external factors, requiring effective wound treatment methods.
- This study introduces a chemokine-loaded biomimetic hydrogel made of Polyvinyl alcohol (PVA) and chitosan (CS), which effectively recruits bone marrow mesenchymal stem cells (BMSCs) to enhance wound healing.
- The hydrogel is biocompatible, meaning it doesn't irritate skin, and its ability to release chemokines promotes fast wound repair without causing scars or negative side effects, making it a promising tool for wound therapy.