Impact of physical indicators on ocular development in preschool children.

Objective: Understanding the impact of early childhood physical growth on visual development is crucial, as this period marks a critical phase for foundational physical and ocular maturation. The aim of the current study was to investigate the associations between the anthropometric indicators of height, weight, and body mass index (BMI), as well as visual acuity, refraction, and ocular biometrics, in Chinese preschool children.

Methods: This cross-sectional study consisted of 1,477 Chinese 3- to 6-year-old preschool children from nine kindergartens in Tongzhou District, Beijing.

Arthroscopic meniscal posterior root repair combined with centralization reduces medial menicus extrusion associated with posterior root tears: One-year clinical outcomes.

Purpose: This study aimed to assess the short-term clinical efficacy of combining posterior meniscal root repair with meniscal centralization technology in the treatment of medial meniscus posterior root tears (MMPRTs) and notable meniscus extrusion.

Methods: In this retrospective analysis, patients aged 43-76 years with only chronic posterior root tears of the medial meniscus and notable extrusion were followed up for 12-14 months.

Inclusion Criteria: (1) persistent medial knee joint pain affecting daily life, presenting with joint space tenderness; (2) showing the ineffectiveness of conservative treatment for a minimum of 3 months; conservative treatment includes non-invasive methods such as nonsteroidal anti-inflammatory drugs, physical therapy and massage, but does not include intra-articular injections.

Permeability Prediction of Nanoscale Porous Materials Using Discrete Cosine Transform-Based Artificial Neural Networks.

The permeability of porous materials determines the fluid flow rate and aids in the prediction of their mechanical properties. This study developed a novel approach that combines the discrete cosine transform (DCT) and artificial neural networks (ANN) for permeability analysis and prediction in digital rock images, focusing on nanoscale porous materials in shale formations. The DCT effectively captured the morphology and spatial distribution of material structure at the nanoscale and enhanced the computational efficiency, which was crucial for handling the complexity and high dimensionality of the digital rock images.

Crashworthiness Study of 3D Printed Lattice Reinforced Thin-Walled Tube Hybrid Structures.

Based on the advantages of thin-walled tubes and lattice structures in energy absorption and improved crashworthiness, a hybrid structure of lattice-reinforced thin-walled tubes with different cross-sectional cell numbers and gradient densities was constructed, and a high crashworthiness absorber with adjustable energy absorption was proposed. The experimental and finite element characterization of the impact resistance of uniform density and gradient density hybrid tubes with different lattice arrangements to withstand axial compression was carried out to investigate the interaction mechanism between the lattice packing and the metal shell, and the energy absorption of the hybrid structure was increased by 43.40% relative to the sum of its individual components.

A New Uniaxial Tensile Model for Foam Metal/Epoxy Interpenetrated Phase Composites.

Foam metal/epoxy interpenetrating phase composite is a new type of composite material with interpenetrating continuity in composition, which exhibits different intrinsic relationships under different stress states in tension and compression, and it is necessary to study the intrinsic relationships in the tensile state in depth. A mesoscopic damage-based tensile intrinsic model is developed, and the elasto-plastic tensile intrinsic equations of the representative volume element are derived based on small deformation theory and total strain theory, as well as the assumptions of equal stress and equal strain. The tensile strengths of nickel-iron foam/epoxy interpenetrated phase composites in three different sizes and their constituent phases were measured, and it was shown in the results that the composite of three-dimensional network interpenetration with high-strength foam metal and epoxy resin formed a weak surface inside the material, and did not significantly improve the tensile strength of the composites.

Vacuum sealing drainage system combined with an antibacterial jackfruit aerogel wound dressing and 3D printed fixation device for infections of skin soft tissue injuries.

Injuries and infections of skin and soft tissue are commonly encountered in primary health care and are challenging to manage. Vacuum sealing drainage (VSD) is generally used in clinical treatment, but current commercial methods of VSD have some disadvantages, such as easy blockage, nonantibacterial effects, and inconvenient curved surfaces. Herein, we report a functional zinc oxide/jackfruit aerogel (ZnO/JFA) composite material that is ultralight, superabsorbent and antibacterial as a new antibacterial VSD wound dressing.

Compression Deformation Prediction of Chiral Metamaterials: A Compression-Shear Coupling Model.

A category of metamaterials consisting of chiral cytosolic elements assembled periodically, in which the introduction of a rotatable annular structure gives metamaterials the ability to deform in compression-shear, has been a focus of research in recent years. In this paper, a compression-shear coupling model is developed to predict the compressive deformation behaviour of chiral metamaterials. This behaviour will be analysed by coupling the rotation of the annular node and the bending characteristics of ligament beam, which are obtained as a function of the length of ligament beam and the angle of rotation at the end of the beam.

Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates.

Premature ovarian insufficiency (POI) is defined as the loss of ovarian activity under the age of 40. Theca cells (TCs) play a vital role during folliculogenesis and TCs dysfunction participate in the pathogenesis of POI. Therefore, transplantation of thecal stem cells (TSCs), which are capable of self-renewal and differentiation into mature TCs, may provide a new strategy for treating POI.

Mechanical Properties of Cemented Particulate Composite: A 3D Micromechanical Model.

Cemented particulate composite is a kind of composite material with high strength, high energy absorption, and multifunctional characteristics, which is widely used in engineering practice. The calculation of the mechanical properties of granular composites based on theoretical methods has always been a topic of discussion. A micromechanical model with a three-dimensional rigid beam-spring network (3D-RBSN) is proposed here.

Uniaxial Compression Mechanical Properties of Foam Nickel/Iron-Epoxy Interpenetrating Phase Composites.

The damage process and failure mechanisms were analyzed by a series of quasi-static compressive experiments of seven materials including pure epoxy (EP), three different PPI (pores per linear inch) foam nickel-iron, and three different PPI foam nickel/iron-epoxy interpenetrating phase composites (IPC). Plotting the stress-strain curves of different materials, their change rules are discussed, then the effective elastic modulus and yield limit of the materials are provided, and the energy absorption properties of different materials are analyzed by the stress-strain curves. It was found that the effective elastic modulus and specific stiffness of the three IPC materials were higher than pure foam nickel-iron.

Mechanical and electronic properties of van der Waals layered hcp PdH.

Mechanical and electronic properties of palladium dihydrides (PdH) as a function of pressure were studied by ab initio calculations based on density functional theory (DFT). The ab initio random structure searching technique was employed for screening potential PdH crystal structures under high pressure. A hexagonal close packed (hcp) phase of PdH with space group P6mc was reported.

Enhancement of flaky graphite cleaning by ultrasonic treatment.

In this study, the aim is to simplify the graphite cleaning process. In order to achieve flotation for graphite effectively, ultrasonic treatment was used as a pre-treatment technique. Flotation tests were conducted using different ultrasound power and ultrasonic treatment time.

Upregulated LINC00565 Accelerates Ovarian Cancer Progression By Targeting GAS6.

Background: Long noncoding RNAs (lncRNAs) have been identified to participate in tumorigenesis. However, the underlying mechanisms of differentially expressed lncRNAs engaged in diseases remain indistinct and need further exploration.

Methods: Raw data files downloaded from TCGA and GEO dataset were used to analyze the differentially expressed lncRNAs and LINC00565 was picked out as the potential oncogene.

LINC01127 promotes the development of ovarian tumors by regulating the cell cycle.

Background: Ovarian cancer is characterized by the high mortality rate and poor prognosis. Nevertheless, the oncogenesis mechanisms of ovarian cancer remain unclear. In our study, we focused on the potential role of lncRNA LINC01127 in the pathogenesis of ovarian cancer and its underlying mechanism.

LncRNAs KB-1836B5, LINC00566 and FAM27L are associated with the survival time of patients with ovarian cancer.

Ovarian cancer (OvCa) is the most common gynecological malignancy type in the United States in 2014. Functions of long non-coding RNAs (lncRNAs) in OvCa have attracted increasing attention from researchers. The present study aimed to identify an lncRNA-based signature for survival prediction in patients with OvCa.

Unveiling the signals from extremely noisy microseismic data for high-resolution hydraulic fracturing monitoring.

Microseismic method is an essential technique for monitoring the dynamic status of hydraulic fracturing during the development of unconventional reservoirs. However, one of the challenges in microseismic monitoring is that those seismic signals generated from micro seismicity have extremely low amplitude. We develop a methodology to unveil the signals that are smeared in the strong ambient noise and thus facilitate a more accurate arrival-time picking that will ultimately improve the localization accuracy.

Formation and electronic properties of palladium hydrides and palladium-rhodium dihydride alloys under pressure.

We present the formation possibility for Pd-hydrides and Pd-Rh hydrides system by density functional theory (DFT) in high pressure upto 50 GPa. Calculation confirmed that PdH in face-centered cubic (fcc) structure is not stable under compression that will decomposition to fcc-PdH and H. But it can be formed under high pressure while the palladium is involved in the reaction.

[Effects of human leukocyte antigen-G on p38 mitogen-activated protein kinase signaling pathway in HTR-8/SVneo cell line].

Objective: To investigate the role of human leukocyte antigen-G (HLA-G) on the invasion and the molecular mechanism involved in this cellular progress in HTR-8/SVneo cell line.

Methods: There were three groups: groups of transfection, negative control and blank control, which corresponding to treatment by HLA-G specific siRNA, negative siRNA and only lipofectamine 2000 using lipofection technology in HTR-8/SVneo cell line. The efficiency of down-regulated of HLA-G was detected by reverse transcription-polymerase chain reaction and western blot analysis in mRNA and protein level, respectively.