Enhanced visible-light-driven photocatalytic degradation of tetracycline wastewater using surfactant-modified Au-loaded CeO nanorods.

The residues of tetracyclines (TCs) antibiotics present significant challenges in terms of contamination and pose a threat to human health. In this study, a cost-effective n-type semiconductor, CeO, were loaded with small amounts of Au nanoparticles were fabricated by one-step hydrothermal method under alkaline conditions in the presence of the surfactant CTAB. Characterization tests revealed that Au/CeO had significant visible light absorption capacity and good e/h separation efficiency.

Engineering Hierarchically Grooved Structures for Enhancing Interfacial Solar Thermal Water Purification.

Inclined interfacial solar evaporators, especially those based on microgrooved Al substrates, show great potential for application in water purification to alleviate the water crisis. However, performance degradation caused by corrosion and contamination seriously affects their service life. To address this issue, a renewable heterojunction with TiO as the inner layer and ZnO as the outer layer is formed on microgrooved Al by atomic layer deposition, which provides effective anticorrosion protection and efficiently kills adhered and planktonic bacteria.

Dihydromyricetin Improves Myocardial Functioning by Influencing Autophagy Through SNHG17/Mir-34a/SIDT2 Axis.

Background Diabetic cardiomyopathy [DCM] is a common and severe complication of Diabetes Mellitus [DM]. Dihydromyricetin [DHM] is a flavonoid compound with potential cardioprotective effects, but the mechanism of DHM in diabetes-induced myocardial damage and autophagy is not fully understood. Objective The objective of this study is to evaluate the effects of DHM on cardiac function and pathological features of DCM, with a particular focus on its impact on the SNHG17/miR-34a/SIDT2 pathway.

Effect of lutein supplementation on blood lipids and advanced glycation end products in adults with central obesity: a double-blind randomized controlled trial.

Central obesity poses a significant health threat. Lutein-rich fruits and vegetables may help manage obesity. Limited evidence suggests that lutein exerts health effects by inhibiting advanced glycation end products (AGEs), but data on its effects in centrally obese individuals are sparse.

Transcriptome and DNA methylation analysis of the goat pineal gland during puberty.

Previous studies have confirmed that methylation regulates gene transcription in the hypothalamus-pituitary-gonadal axis during puberty initiation, but little is known about the regulation of DNA methylation on gene expression in the pineal gland. To screen pineal gland candidate genes related to the onset of goat puberty and regulated by genome methylation, we collected pineal glands from prepubertal and pubertal female goats, then, determined the DNA methylation profile by whole genome bisulfite sequencing and the transcriptome by RNA sequencing on Illumina HiSeqTM2500. We analyzed differentially expressed genes between the Pre group and Pub group using the DESeq2 software (version 1.

Prenatal Silicon Dioxide Nanoparticles Exposure Reduces Female Offspring Fertility Without Affecting Males.

Silicon dioxide nanoparticles (SiO NPs) are widely utilized in biomedicine due to their controllable size and biocompatibility. While previous studies have demonstrated that prenatal exposure to SiO NPs can traverse the placental barrier and induce neurotoxicity in offspring. However, their reproductive toxicity remains unclear.

Rational fabrication of an anionic zinc carboxylate framework as a fluorescent probe for 2,6-pyridinedicarboxylic acid.

Sensitive, rapid and convenient sensing of 2,6-pyridinedicarboxylic acid (DPA, a biomarker for ) is crucial for the screening and diagnosis of anthrax. Metal organic framework (MOF)-based sensors are very promising for sensing DPA; however, the design and construction of high-performance sensors with high specificity and sensitivity is still challenging. In this work, a novel luminescent carboxylate MOF (TTCA-Zn) was assembled and employed specifically for the recognition of DPA.

Establishment of a survival predictive model for patients with two synchronous multiple primary lung cancers: a multicenter cohort analysis.

Background: The prognostic predictors of the synchronous multiple primary lung cancer (SMPLC) still remain unclear, and there is a lack of studies on the prognosis of SMPLC patients excluding those with multifocal ground-glass/lepidic (GG/L) nodules. The aim of this study is to develop an effective model for predicting survival of SMPLC patients.

Methods: In this multicenter cohort study, a total of 831 SMPLC patients presenting for lung cancer resection from January 2004 to January 2018 at five institutions were included for developing and validating a nomogram model.

Insight into the efficient loading and enhanced activity of enzymes immobilized on functionalized UiO-66.

Enzyme immobilization is an effective strategy for achieving efficient and sustainable enzyme catalysis. As a kind of promising enzyme-loading materials, the systematic research on zirconium based metal organic frameworks (Zr-MOFs) about immobilization performance at molecular level is still in its initial stage. In this work, UiO-66 was functionalized with various groups (-H, -NH, -COOH, -OH, -2OH) for the immobilization of cytochrome c (Cyt c) and antioxidant enzyme catalase (CAT).

Four three-dimensional rare earth metal - organic framework fluorescent sensor for efficient detection of gentamicin sulfate and Fe.

Excessive use of gentamicin sulfate can cause severe nephrotoxicity and ototoxicity, abnormal levels of Fe intake can also cause serious damage to body. Therefore, establishing a fast and accurate detection method for the above-mentioned substances is of great significance. However, traditional detection methods such as high-performance liquid chromatography still have certain problems such as high cost and complex operation.

Fabrication of a Terbium-Functionalized Cadmium Organic Framework with Proper Energy Levels as a Ratiometric Probe of an Anthrax Biomarker.

Anthrax bacillus is a very dangerous zoonotic pathogen that seriously endangers public health. Rapid and accurate qualitative and quantitative detection of its biomarkers, 2,6-dipicolinic acid (DPA), is crucial for the prevention and treatment of this pathogenic bacterium. In this work, a novel Cd-based MOF (TTCA-Cd) has been synthesized from a polycarboxylate ligand, [1,1':2',1″-terphenyl]-4,4',4″,5'-tetracarboxylic acid (HTTCA), and further doped with Tb(III), forming a dual-emission lanthanide-functionalized MOF hybrid (TTCA-Cd@Tb).

Effects of Vaccination against Recombinant FSH or LH Receptor Subunits on Gonadal Development and Functioning Male Rats.

Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) play key roles in regulating testosterone secretion and spermatogenesis in male mammals, respectively, and they maintain the fertility of male animals by binding to their corresponding receptors. We designed and prepared a recombinant LH receptor (LHR) subunit vaccine and a recombinant FSH receptor (FSHR) subunit vaccine and used male Sprague Dawley (SD) rats as a model to examine their effects on testicular development, spermatogenesis, and testosterone secretion in prepubertal and pubertal mammals. Both vaccines (LHR-DTT and FSHR-DTT) significantly decreased the serum testosterone level in prepubertal rats ( < 0.

Sestrin2 and Sestrin3 protect spermatogenesis against heat-induced meiotic defects†.

Heat stress induces testicular oxidative stress, impairs spermatogenesis, and increases the risk of male infertility. Recent studies have highlighted the antioxidative properties of the Sestrins family in reducing cellular oxidative damage. However, the role of Sestrins (Sestrin1, 2, and 3) in the testicular response to heat stress remains unclear.

Constructing a novel type-Ⅱ ZnO/BiOCOOH heterojunction microspheres for the degradation of tetracycline and bacterial inactivation.

A novel ZnO/BiOCOOH microsphere photocatalyst with a type-Ⅱ mechanism was developed for the first time. This strategy was accomplished by immobilizing ZnO onto 3D BiOCOOH microspheres via a single-step hydrothermal synthesis method. The ability to degrade tetracycline (TC) in water under visible light and inactivate bacteria of as-catalyst were analyzed.

Exploring the action mechanism of Jinxin oral liquid on asthma by network pharmacology, molecular docking, and microRNA recognition.

Using network pharmacology, molecular docking, and microRNA recognition, we have elucidated the mechanisms underlying the treatment of asthma by Jinxin oral liquid (JXOL). We began by identifying and normalizing the active compounds in JXOL through searches in the traditional Chinese medicine systems pharmacology database, SwissADME database, encyclopedia of traditional Chinese medicine database, HERB database, and PubChem. Subsequently, we gathered and standardized the targets of these active compounds from sources including the encyclopedia of traditional Chinese medicine database, similarity ensemble approach dataset, UniProt, and other databases.

Terbium doping and energy level modification of zirconium organic frameworks as probes for the improved determination of histamine and visual inspection of food freshness.

Food safety is a common concern among people, and the development of high-performance food freshness detection technology is crucial, but is still highly challenging. Fluorescent sensing based on metal organic frameworks is a promising technology to tackle this issue. In this work, three UiO-66 type Zirconium organic frameworks (ZrOFs) which are functionalized with varying numbers of hydroxyl groups to alter the energy levels, and partial replacement of Zirconium(IV) by Terbium(III) ions to introduce additional emitting centers, were explored as probes for the sensing of Histamine (His).

Identification of the matrix metalloproteinase (MMP) gene family in Japanese flounder (Paralichthys olivaceus): Involved in immune response regulation to temperature stress and Edwardsiella tarda infection.

The Matrix metalloproteinase (MMP) gene family is responsible for regulating the degradation of Extra Cellular Matrix (ECM) proteins, which are important for physiological processes such as wound healing, tissue remodeling, and stress response. Although MMPs have been studied in many species, their role in immune response in Japanese flounder (Paralichthys olivaceus) is still not fully understood. This study conducted a comprehensive analysis of MMPs in flounder, including gene structures, evolutionary relationships, conserved domains, molecular evolution, and expression patterns.

Mechanistic investigation of intensified separation of molybdenum(VI) and vanadium(V) using polymer inclusion membrane electrodialysis.

The main challenge in separating molybdenum(VI) and vanadium(V) which have similar properties results in great difficulties in the green recycling of hazardous spent catalysts. Here, selective facilitating transport and stripping are integrated into the polymer inclusion membrane electrodialysis process (PIMED) to separate Mo(VI) and V(V) to overcome the complicated co-extraction and stepwise-stripping in conventional solvent extraction. The influences of various parameters, the selective transport mechanism, and respective activation parameters were systematically investigated.

Colorimetric and visual determination of iodide ions via morphology transition of gold nanobipyramids.

The gold nanobipyramids (Au NBPs) are widely used in the analytical detection of biochemistry due to their unique localized surface plasmon resonance (LSPR) properties. In our developed approach, I in kelp was detected by etching Au NBPs in the presence of IO. Under acidic conditions, IO reacted rapidly with I to form I, subsequently I reacted with I to form the intermediate I.

Effect of GnRH immunocastration on immune function in male rats.

The present study aimed to reveal the effects of immunocastration on the development of the immune system in rats. Seventy rats were randomly assigned into two groups: Control (n = 35) and immunized (n = 35). Twenty-day-old rats were immunized with gonadotropin-releasing hormone (GnRH) and booster immunization was administered every two weeks (three immunizations in total).

Morphological and Molecular Functional Evidence of the Pharyngeal Sac in the Digestive Tract of Silver Pomfret, .

The pharyngeal sac is a comparatively rare organ in the digestive tract among teleost fishes. However, our understanding of this remarkable organ in the silver pomfret () is limited. In the present study, we examined the various morphological and histological characteristics of the pharyngeal sac using histochemical techniques and electron microscopy.

Replacement of long-segment ureteral defect with tapered demucosalized ileum: medium-term outcomes of 4 patients.

Purpose: Repair of long-segment ureteral defect (LSUD) is challenging. Currently available procedures carry some potential complications. We modified the ileal graft by tapering the wall and stripping the mucosa to combat associated pitfalls and first reported the medium-term outcomes of 4 patients.

Er-xian decoction drug-containing serum promotes Mc3t3-e1 cell proliferation and osteogenic differentiation via regulating BK channel.

Ethnopharmacological Relevance: Er-xian Decoction (EXD) is a well-known prescription widely used to prevent and treat climacteric syndrome and osteoporosis in China. BK channel positively affects osteoblast bone formation in vitro. However, it is still unclear whether the effect of EXD on promoting osteoblasts osteogenic differentiation is related to BK channel.

Functionalized Zirconium Organic Frameworks as Fluorescent Probes for the Detection of Tetracyclines in Water and Pork.

The overuse of tetracyclines (TCs) in livestock breeding may cause a series of health and environmental problems. It is necessary to develop more accurate, convenient, and rapid sensing methods toward TCs, but it is still very challenging. In this work, three isostructural zirconium organic frameworks (Zr-MOFs) have been investigated as probes for the fluorescent sensing of TCs in water.