Publications by authors named "Huige Wu"
Biomed Pharmacother
August 2023
Article Synopsis
- Sepsis is a serious global health issue with high mortality rates, prompting research into the novel drug candidate ASK0912 for its protective effects during sepsis caused by Acinetobacter baumannii in mice.!
- The study found that ASK0912 significantly improved survival rates, maintained body temperature, reduced bacterial loads, and prevented organ damage in septic mice administered a low dose of 0.6 mg/kg.!
- Additionally, ASK0912 reduced elevated cytokine levels, thereby mitigating inflammation and supporting better immune response in sepsis-affected mice, highlighting its potential as a treatment option.!
