Publications by authors named "Huifeng Diao"
Article Synopsis
- - This study investigates how the LINC00663/EBF1/NR2F1 pathway influences inflammation and blood vessel formation (angiogenesis) in bladder cancer.
- - Researchers performed various experiments, including cell tests and animal studies, showing that higher levels of LINC00663 and NR2F1 are linked to more aggressive cancer traits, such as cell growth and invasiveness.
- - Silencing LINC00663 led to decreased NR2F1 levels and reduced cancer-related processes, suggesting that LINC00663 plays a crucial role in promoting inflammation and angiogenesis in bladder cancer through its regulation of NR2F1 via EBF1.
The study aimed to investigate the significant potential role of miR-877-5p in Prostate cancer. The expression levels of miR-877-5p and forkhead box M1 (FOXM1) mRNA were detected by qRT-PCR. The prognostic significance of miR-877-5p in prostate cancer was investigated using Kaplan Meier analysis.
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- Overexpression of eIF5A2 in various cancers is linked to increased tumor cell migration and invasion, raising questions about its role as a treatment target in prostate cancer (PCa).
- This study utilized specific RNA techniques to lower eIF5A2 levels in prostate cancer cells and in animal models, assessing effects on cell behavior and tumor progression.
- Findings revealed that reducing eIF5A2 led to decreased cell migration, increased apoptosis, and lower tumor growth and metastasis, suggesting that targeting eIF5A2 may be a promising approach for PCa treatment.