Evaluation of the effects of three different processing methods of aconite on rat metabolites based on high-coverage pseudotargeted metabolomics.

Aconite is the processed product of the seed root of Aconitum carmichaelii Debx. Aconite is a commonly used traditional Chinese medicine, which is generally used after processing. Black aconite, light aconite, and salted aconite are three different processed aconite products.

The Pseudotargeted Metabolomics Study on the Toxicity of Fuzi Using Ultraperformance Liquid Chromatography Tandem Mass Spectrometry.

Fuzi is commonly used in traditional Chinese medicine. Clinical Fuzi poisoning cases have frequently been reported. Glycyrrhizae Radix is often used to alleviate Fuzi's toxicity.

Soundscape Evaluation Outside a Taoist Temple: A Case Study of Laojundong Temple in Chongqing, China.

The unique architectural form and religious background of Taoist buildings can lead to a special acoustic environment, but there is a lack of research on the soundscape evaluation of Taoist buildings. Laojundong Taoist Temple was selected as the research site. The psychological and physiological responses of Taoist priests and ordinary people, and strategies for soundscape renovation were investigated by conducting field measurements, interviews, soundwalks, and audio−visual experiments.

Effects of triangle grass decoction on bone metabolism in rats with chronic kidney disease complicated with mineral and bone abnormalities.

Ethnopharmacological Relevance: Triangle grass is a liliaceous Chlorophytum perennial herb of ChlorophytumlaxumR.Br. It is distributed mainly in Guangdong and Guangxi Provinces of China.

Pharmacokinetic Profiling of Butylidenephthalide and Alisol B in Danggui-Shaoyao-San in Rats.

Background And Objective: Danggui-Shaoyao-San (DSS), a famous Chinese formula, has been widely used to treat gynecological disorders since ancient times and has recently showed efficacy in treating Alzheimer's disease. Butylidenephthalide (BDPH) and alisol B (ALI) are recognized as the primary active ingredients of DSS. The objectives of the present study were to evaluate the pharmacokinetic comparative study of BDPH and ALI in herbal extracts and their purified forms.

Whole genome sequencing analysis of lung adenocarcinoma in Xuanwei, China.

Background: The lung cancer mortality rate in Xuanwei city is among the highest in China and adenocarcinoma is the major histological type. Lung cancer has been associated with exposure to indoor smoky coal emissions that contain high levels of polycyclic aromatic hydrocarbons; however, the pathogenesis of lung cancer has not yet been fully elucidated.

Methods: We performed whole genome sequencing with lung adenocarcinoma and corresponding non-tumor tissue to explore the genomic features of Xuanwei lung cancer.

Gene expression profiling of lung adenocarcinoma in Xuanwei, China.

The morbidity and mortality of lung cancer in Xuanwei, China, are the highest in the world. This study attempts to identify differentially expressed genes (DEGs) related to lung adenocarcinoma in Xuanwei. The expression profiles of eight paired lung adenocarcinoma tissues and corresponding nontumor tissues were acquired by microarrays.

Genomic structure and promoter functional analysis of GnRH3 gene in large yellow croaker (Larimichthys crocea).

Gonadotropin-releasing hormone III (GnRH3) is considered to be a key neurohormone in fish reproduction control. In the present study, the cDNA and genomic sequences of GnRH3 were cloned and characterized from large yellow croaker Larimichthys crocea. The cDNA encoded a protein of 99 amino acids with four functional motifs.

[Optimization extraction conditions of triphyllin A in Pronephrium triphyllum].

Objective: To optimize the extraction conditions for triphyllin A in Pronephrium triphyllum.

Methods: The content of triphyllin A in the Pronephrium triphyllum was determined by HPLC. Concentration and volume of the alcohol,time and times of the extraction were assayed by orthogonal test to detect their influences on the extraction rate of triphyllin A in the Pronephrium triphyllum.

[The effects of dieda zhentong liquid on ear microcirculation of rabbit].

Objective: To observe the effects of Dieda Zhentong Liquid (DDZTL) on ear microcirculation of rabbits.

Methods: With microcirculation apparatus, caliber of micrangium, velocity and volume of blood flow were detected in experimental groups.

Results: The volume of blood flow of DDZTL group without Chlorophytum laxum haven't an increase compared with that of the group without administering the medicinal liquid.