An in-line Mach-Zehnder Interferometer Using Thin-core Fiber for Ammonia Gas Sensing With High Sensitivity.

Ammonia is an important indicator among environmental monitoring parameters. In this work, thin-core fiber Mach-Zehnder interferometer deposited with poly (acrylic acid) (PAA), poly (allyamine hydrochloride) (PAH) and single-walled carbon nanotubes (SWCNTs-COOH) sensing film for the detection of ammonia gas has been presented. The thin-core fiber modal interferometer was made by fusion splicing a small section of thin-core fiber (TCF) between two standard single mode fibers (SMF).

Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies.

Background: Conventional prenatal screening tests, such as maternal serum tests and ultrasound scan, have limited resolution and accuracy.

Methods: We developed an advanced noninvasive prenatal diagnosis method based on massively parallel sequencing. The Noninvasive Fetal Trisomy (NIFTY) test, combines an optimized Student's t-test with a locally weighted polynomial regression and binary hypotheses.