Physicochemically Cross-linked Injectable Hydrogel: an Adhesive Skin Substitute for Burned Wound Therapy.

Burns carry a large surface area, varying in shapes and depths, and an elevated risk of infection. Regardless of the underlying etiology, burns pose significant medical challenges and a high mortality rate. Given the limitations of current therapies, tissue-engineering-based treatments for burns are inevitable.

Multifunctional Porous Bilayer Artificial Skin for Enhanced Wound Healing.

Meeting the exacting demands of wound healing encompasses rapid coagulation, superior exudate absorption, high antibacterial efficacy, and imperative support for cell growth. In this study, by emulating the intricate structure of natural skin, we prepare a multifunctional porous bilayer artificial skin to address these critical requirements. The bottom layer, mimicking the dermis, is crafted through freeze-drying a gel network comprising carboxymethyl chitosan (CMCs) and gelatin (GL), while the top layer, emulating the epidermis, is prepared via electrospinning poly(l-lactic acid) (PLLA) nanofibers.

Empirical study of physicochemical and spectral properties of Cu-containing chelate-based ionic liquids.

The physicochemical properties including melting point, density, viscosity, conductivity, and surface tension as well as spectral properties such as infrared and EPR spectra of the chelate-based ILs [Cmim][Cu(F-acac)] (n = 6, 8, 10, 12, 14) were studied as functions of temperature and chain length. The thermodynamic properties such as the standard molar entropy and crystal energy were estimated by Glasser's theory, the molar enthalpy of vaporization was calculated by Kabo's method, and the ionicity was estimated by the Walden rule. Compared with the common ILs, the chelate-based ILs have larger molecular volume, larger density, smaller crystal energy, poorer ionicity and larger enthalpy of vaporization.