Effects of Sintilimab Plus Radiotherapy on Levels of Spondin-2 and Glucose Transporter-1 in Patients with Cervical Cancer.

Purpose: We aimed to evaluate the effects of sintilimab plus radiotherapy on levels of Spondin-2 and glucose transporter-1 (Glut-1) in patients with cervical cancer.

Patients And Methods: A total of 112 patients with cervical cancer treated from January 2019 to January 2021 were selected in this randomized control trial and divided into a control group (n = 56) and a study group (n = 56) using the random number table method. Chemotherapy using docetaxel + cisplatin was performed for both groups, based on which the control group was given radiotherapy (external conformal radiotherapy + intracavitary irradiation), and the study group received sintilimab plus radiotherapy.

Relationship Between Occupational Noise Exposure and Gestational Hypertension in Pregnant Women in Taizhou City: Cross-Sectional Study.

Objective: In view of the hazards of occupational noise exposure, this study investigated the relationship between occupational noise exposure and gestational hypertension in Taizhou City, Zhejiang Province, China to provide inspiration and reference for reducing the occurrence of gestational hypertension.

Methods: This cross-sectional study analyzed the clinical data of 316 pregnant women in Taizhou City admitted to Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University from May 2020 to May 2023. In accordance with Acoustic Environment Quality Standards (GB3096-2008), 60 dB was used as the cut-off point.

Golgi Phosphoprotein 3 Promotes Cervical Cancer Progression via Wnt/β-catenin Mediated Epithelial-Mesenchymal Transition.

Objective: Cervical cancer (CC) is one of the fatal malignancies affecting the life expectancy of women worldwide. Golgi Phosphoprotein 3 (GOLPH3) has been shown to play a key role in the development of various tumors. However, the role of GOLPH3 in the development of CC is unclear.

The Clinical Efficacy of Autologous Platelet-Rich Plasma Interventional Circulatory Perfusion Combined with Radiofrequency Ablation and Thermocoagulation in the Treatment of Discogenic Low Back Pain.

Objective: In this study, we aimed to explore the efficacy of the autologous platelet-rich plasma (PRP) interventional circulatory perfusion combined with radiofrequency ablation and thermocoagulation (RFAT) in the treatment of discogenic low back pain (DLBP).

Methods: From January 2020 to November 2022, 158 patients of the Second Affiliated Hospital of Nanchang University were selected as the study subjects, and 24 patients met the exclusion criteria. The 134 patients who met the inclusion criteria were divided into 65 patients in the control group (3 patients lost to follow-up) and 69 patients in the observation group (5 patients lost to follow-up), so 126 patients were actually completed the study, including 62 patients in the control group and 64 patients in the observation group.

Investigation of Mandarin Word Production in Children and Adults: Evidence from Phonological Priming with Non-words.

Using a cross-modal picture-word interference (PWI) task, we examined phonological representations and encoding in Mandarin-speaking children and adults. Pictures of monosyllabic words were presented visually, with auditory primes presented before, concurrent with, or after the picture's appearance (SOA -200, -100, 0, +150). Primes were related to the targets in terms of Onset, Rhyme, Tone, Onset and Tone, Rhyme and Tone, or were unrelated.

Effect of Two Different Sugarcane Cultivars on Rhizosphere Bacterial Communities of Sugarcane and Soybean Upon Intercropping.

Intercropping of soybean and sugarcane is an important strategy to promote sustainable development of the sugarcane industry. In fact, our understanding of the interaction between the rhizosphere and bacterial communities in the intercropping system is still evolving; particularly, the influence of different sugarcane varieties on rhizosphere bacterial communities in the intercropping process with soybean, still needs further research. Here, we evaluated the response of sugarcane varieties ZZ1 and ZZ9 to the root bacterial community during intercropping with soybean.

Response of Soil Fungal Community to Drought-Resistant Transgenic Sugarcane.

Drought limits crop productivity, especially of sugarcane, which is predominantly grown in the subtropical parts of China. Soil microbes perform a wide range of functions that are important for plant productivity and responses to drought stress, and fungi play an important role in plant-soil interactions. The gene of sugarcane, , is involved in regulating the response to drought stress.

Haemoglobin A Levels Constantly Below Lower Reference Limit in a Diabetic Patient With Microcytic Anaemia.

Introduction: Haemoglobin A (A), as a parameter of long-term glycaemic control, has been adopted to guide diabetic therapy all over the world. However, falsely high or low A could be troublesome in daily practice.

Case Description: A 75-year-old male diabetic patient affected by a reasonably inferred life-long history of microcytic anaemia was found to have abnormally low A values in the previous 5 months.

SPP1 inhibition improves the cisplatin chemo-sensitivity of cervical cancer cell lines.

Purpose: Cisplatin (DDP)-based chemotherapy is a standard strategy for cervical cancer, while chemoresistance remains a huge challenge. In the present study, we aimed to explore the effects of SPP1 on the proliferation and apoptosis rate of the HeLa cervical cancer cell line with cisplatin (DDP) resistance.

Methods: Microarray analysis was employed to select differentially expressed genes in cervical cancer tissues and adjacent tissues.

Long noncoding RNA OPA-interacting protein 5 antisense transcript 1 upregulated SMAD3 expression to contribute to metastasis of cervical cancer by sponging miR-143-3p.

Objectives: SMAD3 is pivotal in the biology functions of various tumors. This study is aiming to study the relationship among SMAD3, long noncoding RNAs (lncRNAs) OPA-interacting protein 5 antisense transcript 1 (OIP5-AS1), and miR-143-3p, and their effects on cervical cancer.

Methods: In our research, real-time polymerase chain reaction and western blot assay were conducted to detect the expression level of messenger RNA and protein in tumor tissues and cells.

Executive Function in Preschoolers with Primary Language Impairment.

Purpose: The purpose of this study was to evaluate whether preschoolers with primary language impairment (PLI) show deficits in executive function (EF) compared with their peers with typical development (TD) when inhibition, updating, and mental-set shifting are examined using both linguistically based and visually based tasks.

Method: Twenty-two 4- and 5-year-old preschoolers with PLI and 30 preschoolers with TD completed 2 sets of computerized EF tasks: 3 that were linguistically based and 3 that were visually based. This permitted us to test the hypothesis that poor performance on EF tasks in preschoolers with PLI results from impaired language rather than impaired EF.

Fluoride adsorption on carboxylated aerobic granules containing Ce(III).

Aerobic granules (AG) were carboxylated and Ce(III) was incorporated to obtain modified granuels (Ce(III)-MAG) for removal of fluoride from aqueous solutions. The Ce(III)-MAG was characterized by SEM, FTIR, XRD and pH(pzc), and the introduction of carboxyl groups and Ce(III) was confirmed. The adsorption capacity of Ce(III)-MAG for fluoride was 45.

One-handed helical double stranded polybisnorbornenes.

Helical double stranded polymers incorporated with a covalently bound chiral ferrocene linker are synthesised and characterized by CD spectra and STM images and molecular dynamics simulations.

Electrochemical oxidation of double-stranded polybisnorbornenes containing linearly aligned ferrocene linkers.

Seventy percent of the ferrocene moieties in double-stranded polybisnorbornenes containing linearly aligned ferrocene linkers are oxidised and each of the neighbouring monomeric units in these polymers may strongly interact with each other; the oxidised form of has been shown to be antiferromagnetic.