Efficacy and Safety of Expanded Polytetrafluoroethylene Implantation in the Correction of Long-Term Posttraumatic Enophthalmos.

Summary: Long-term enophthalmos is a common orbital fracture sequela. Various autografts and alloplastic materials have been studied in posttraumatic enophthalmos repair. However, expanded polytetrafluoroethylene (ePTFE) implantation in late enophthalmos repair has rarely been reported.

Application of Segmented Template in Three-Dimensionally Guided Mandibular Angle Osteotomy.

Background: The procedure of mandibular angle osteotomy (MAO) via an intraoral approach is challenging and experience-dependent due to the limited field of view and inadequate operational space. Uncertainty about the osteotomy line and plane can lead to severe complications. A three-dimensional printed guidance template based on a computer-assisted preoperative simulation is a potential solution to this problem.

A Single-Blinded Prospective Study on Using Botulinum Toxin Type A for Reducing Alar Mobility.

Background: With widespread utilization of instant social media, people desire a minimally invasive treatment to improve alar dynamic aesthetic, but few practical procedures on reducing alar mobility have been conducted.

Objectives: This study aimed to verify the effects of botulinum toxin on reducing nasal alar mobility and provide a supplemental treatment of rhinoplasty.

Methods: This single-blind prospective study included a cohort of 20 participants with the desire to improve their alar dynamic aesthetic.

Midfacial Soft Tissue Changes After Reduction Malarplasty: A Computed Tomographic Study.

Background: The reduction malarplasty has become one of the most popular esthetic surgeries among Asian women to improve facial contour. However, it is still controversial whether midfacial soft tissue changes after surgery, and more studies are needed.

Methods: This retrospective observational study reviewed 30 patients who underwent L-shaped reduction malarplasty during January 2018 and August 2019.

MEF/KSF-conditioned culture medium: An effective method for culture of mouse dermal papilla cells with osteogenic differentiation potential.

Hair follicle stem cells are pluripotent and have a self-renewal capacity and multi-differentiation potential . As hair follicle stem cells can be easily sampled from the skin and hair of clinical patients at a considerable quantity, these cells have potential applications in wound repair and skin tissue engineering. Effective approaches for the culture and amplification of mouse hair follicle stem cells, as well as the osteogenic differentiation potential and cell source when obtaining mouse-separated cells were examined.

A novel p.Pro871Leu missense mutation in SPECC1L gene causing craniosynostosis in a patient.

Introduction: Craniosynostosis is one of the most common craniofacial abnormalities. It involves premature closure of one or more cranial sutures. Mutations in many genes have been and continue to be identified in patients.

BMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways.

Bone has a remarkable potential for self-healing and repair, yet several injury types are non-healing even after surgical or non-surgical treatment. Regenerative therapies that induce bone repair or improve the rate of recovery are being intensely investigated. Here, we probed the potential of bone marrow stem cells (BMSCs) engineered with chemically modified mRNAs (modRNA) encoding the hBMP-2 and VEGF-A gene to therapeutically heal bone.

A Study on Tuberculosis Classification in Chest X-ray Using Deep Residual Attention Networks.

The introduction of deep learning techniques for the computer-aided detection scheme has shed a light for real incorporation into the clinical workflow. In this work, we focus on the effect of attention in deep neural networks on the classification of tuberculosis x-ray images. We propose a Convolutional Block Attention Module (CBAM), a simple but effective attention module for feed-forward convolutional neural networks.

Postoperative Complications of Box-Shift Osteotomy for Orbital Hypertelorism.

Objective: To summarize and analyze the postoperative complications of box-shift osteotomy performed at our center for Chinese orbital hypertelorism patients from 2008 to 2017.

Method: This retrospective study reviews the records of 78 patients with complete medical records and at least 2 years of postoperative follow-up data. Both radiologic and anthropometric assessments were conducted before, 1 month after and 2 years after surgery to evaluate the bony and soft-tissue alterations.

A Novel Method to Enhance Dynamic Rhinoplasty Outcomes: Double "V" Carving for Alloplastic Grafts.

Augmentation rhinoplasty is one of the most common plastic surgery procedures performed in Asia. Most Asian patients desire not only a natural-looking nose but also a nose with natural feel. Achieving such rhinoplasty outcomes with grafts has been a challenge for surgeons due to rigidity of grafting material.

Surgical Correction of Proptosis in Craniofacial Benign Bone Lesions Involving the Orbit.

Craniofacial bone lesions involving the orbit are often associated with symptoms, including proptosis, orbital dystopia, and overall facial asymmetry. Fibrous dysplasia and osteoma are the 2 most commonly observed bone tumors in the craniofacial area. Nine patients with either craniofacial fibrous dysplasia or osteoma and an unacceptable aesthetic appearance were treated from January 2015 to July 2016.

Tetrahydroxystilbene Glucoside Effectively Prevents Apoptosis Induced Hair Loss.

The effect of against hair loss has been widely recognized. 2,3,5,4'-Tetrahydroxystilbene-2-O--D-glucoside (TSG) is the main component of ; however, its role in hair regeneration has not been established. To evaluate the hair growth-promoting activity of TSG, depilated C57BL/6J mice were topically treated with normal saline, TSG, Pifithrin-, Minoxidil for 2 weeks.

Recombinant mouse periostin ameliorates coronal sutures fusion in Twist1 mice.

Background: Saethre-Chotzen syndrome is an autosomal dominantly inherited disorder caused by mutations in the twist family basic helix-loop-helix transcription factor 1 (TWIST1) gene. Surgical procedures are frequently required to reduce morphological and functional defects in patients with Saethre-Chotzen syndrome. Therefore, the development of noninvasive procedures to treat Saethre-Chotzen syndrome is critical.

Effect of inhomogeneity of the electrospun fibrous scaffolds of gelatin/polycaprolactone hybrid on cell proliferation.

In this article, gelatin (GT) and polycaprolactone (PCL) blended with a weight ratio of 50:50 were dissolved in the trifluoroethanol (TFE) or the acetic acid-doped TFE solvent system (0.2% relative to TFE) to prepare fibrous scaffolds of GT/PCL with different compositional and morphological homogeneities (denoted as the group 1 and the group 2 scaffolds) by electrospinning. The morphology and composition of the two groups of fibrous scaffolds were examined by scanning electron microscopy and Fourier transform infrared spectroscopy, respectively.

The influence of Gelatin/PCL ratio and 3-D construct shape of electrospun membranes on cartilage regeneration.

Scaffolds play an important role in directing three-dimensional (3-D) cartilage regeneration. Our recent study reported the potential advantages of electrospun gelatin/polycaprolactone (GT/PCL) membranes in regenerating 3-D cartilage. However, it is still unknown whether the changes of GT/PCL ratio have significant influence on 3-D cartilage regeneration.

Engineering of epidermis skin grafts using electrospun nanofibrous gelatin/ polycaprolactone membranes.

Skin engineering provides a new strategy for treating a wide variety of skin defects. In particular, electrospun nanofibrous membranes have been used as carriers for epidermis engineering. The aim of this study was to investigate the feasibility of a modified gelatin and polycaprolactone (GT/PCL) electrospun membrane for epidermis engineering.

Participation of CD34-enriched mouse adipose cells in hair morphogenesis.

Adipose-derived stromal vascular fraction (SVF) cells are heterogeneous in nature, containing a number of different cell types. Recent studies indicate that CD34 may be a specific marker for adipose-derived mesenchymal stem cells (ADMSCs). Using their participation in hair morphogenesis as a model, the multi-differentiation potential of adult stem cells was investigated.

Purification of Schwann cells from adult rats by differential detachment.

Differential detachment by collagenase treatment is a new and efficient method for Schwann cell (SC) purification. As its effect on adult animals remains unclear, we have investigated the possibility of SC purification from adult rats. To avoid any systematic bias, Schwann cell purity before and after purification were compared by morphology, immunostaining of P75(NTR) and S100 and flow cytometric analysis.

3D computerized segmentation of lung volume with computed tomography.

Three-dimensional (3D)-based detection and diagnosis has an important role for significantly improving the detection and diagnosis of lung cancer upon computed tomography (CT). This report presents a 3D-based method for segmenting and visualizing lung volume by using CT images. An anisotropic filtering method was developed on CT slices to enhance the signal-to-noise ratio, and a wavelet transform-based interpolation method was used combined with volume rendering to construct the 3D volumetric data based on entire CT slices.