Publications by authors named "Hui-jie Wan"
Aim: To prepare the compound danshen pH-dependent delayed release pellets and filled them in capsules and then study thier pharmacodynamics.
Methods: The pH-dependent delayed release pellets were prepared by coating with HPMC, Eudragit L-30D-55 and Eudragit L100-Eudragit S100 (1:6), separately, and mixed in proper proportion to prepare the two pH-dependent delayed release systems T1 and T2. The release of delayed release pellets was determined according to the method of China Pharmacopoeia (2000) in the simulated gastrointestinal pH conditions.