Theacrine, a Potent Antidepressant Purine Alkaloid from a Special Chinese Tea, Promotes Adult Hippocampal Neurogenesis in Stressed Mice.

Daily intake of tea has been known to relate to a low risk of depression. In this study, we report that a special variety of tea in China, var. (), possesses antidepressant effects but with less adverse effects as compared to traditional tea .

Comprehensive analysis of gene expression and DNA methylation data identifies potential biomarkers and functional epigenetic modules for lung adenocarcinoma.

Lung cancer has one of the highest mortality rates of malignant neoplasms. Lung adenocarcinoma (LUAD) is one of the most common types of lung cancer. DNA methylation is more stable than gene expression and could be used as a biomarker for early tumor diagnosis.

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations.

Objective: This study aimed to examine the association of clinical prognostic factors with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer (NSCLC) patients.

Methods: The demographic and clinical characteristics of 94 patients with stage IV NSCLC were retrospectively reviewed, and the association between clinical factors and EGFR-TKIs efficacy was evaluated.

Results: Of the 94 stage IV NSCLC patients enrolled in this study, a 74.

[Study on index components and fingerprints of crude and processed Siegesbeckia Herbs].

The change of kirenol, darutigenol and darutoside in Siegesbeckia and its first to ninth processed products were studied, and the ten fingerprints were compared, which provided the experimental basis for the study of Siegesbeckia processing tech- nology. The samples were analysed by HPLC on a SunFire-C18 column (4.6 mm x 150 mm, 5 μm) with gradient elution of acetonitrile (0.

Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats.

Background: Heavy tea consumption is suggested to be unsuitable for hypertensive people. However, the bioactive substances in different varieties of tea leaves are very different. This study compares the effects of three Chinese teas - C.

[Experimental research of effect of crude and processed Herba Siegesbeckiae on anti-inflammation and anti-rheumatism].

Objective: To find out the specialities of the effect of crude and processed Herba Siegesbeckiae on anti-inflammation and anti-rheumatism.

Method: Experiments were made on rats with swelling foot induced by carrageenin; experiments were made on mice with swelling ear induced by xylol; experiments were made on rats with chronic granuloma; experiments were made on rats with adjuvant arthritis.

Result: Foot swelling induced by carrageenin could be diminished with crude and processed Herba Siegesbeckiae at 6.