Publications by authors named "Hui-Zheng Zhang"
Article Synopsis
- The study evaluated the efficacy of the Xpert MTB/RIF assay for quickly diagnosing Tuberculosis (TB) and detecting rifampicin resistance in patients with extrapulmonary TB (EPTB) by comparing it to traditional culture methods.
- The Xpert MTB/RIF assay was tested on 1,614 extrapulmonary specimens and showed high sensitivity and specificity, although sensitivity varied based on the type of specimen.
- The findings suggest that Xpert MTB/RIF is a rapid and effective technique for diagnosing EPTB and detecting drug resistance, especially when used alongside drug susceptibility testing for identifying multi-drug resistant TB (MDR-TB).
Objective: To compare the influence of traditional Chinese compound recipes (TCCRs) with different efficacy on body weight, tumor weight and immune function in H22 cancer-bearing mice.
Methods: H(22) cancer-bearing mice were chosen to observe the effects of TCCRs with different efficacy on tumor growth inhibition and detect the proliferation function of T lymphocytes, the activity of natural killer (NK) cells, the changes of T lymphocytes and the content of interferon-gamma (IFN-gamma)and interleukin-4 (IL-4).
Results: Tumor weight of H(22) cancer-bearing mice in Yidu Gongdu Recipe (YDGDR, a compound traditional Chinese herbal medicine using poison as an antidote for poison)-treated group was obviously lighter than that in the other TCCR-treated groups and the tumor inhibition rate in YDGDR-treated group was 65.
[Study of HLA molecules and its associated genes expression in human ovarian cancer cells].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2003
Aim: To explore the correlation between the expressions of HLA gene and its related gene, and expression of class II transactivator (CIITA) gene induced by IFN-gamma in human ovarian cells.
Methods: The expression of HLA molecule in the tumor cells was detected by Western blot, immunohistochemical staining and flow cytometry. The expressions of transporters associated with antigen processing (TAP), low molecular weight peptides (LMP), and CIITA genes were analyzed by RT-PCR.