An improved method for the preparation of Ginsenoside Rg5 from ginseng fibrous root powder.

Ginsenoside-Rg5, which is derived from high temperature-processed ginseng, exhibits beneficial health effects. In the present study, ginsenoside-Rg5 was directly and rapidly prepared through the extraction of ginseng fibrous root powder (GFRP) at atmospheric pressure. The results showed that the highest extraction yield (3.

NagR Is a Pleiotropic and Dual Transcriptional Regulator in .

NagR, belonging to the GntR/HutC family, is a negative regulator that directly represses the and genes, which are involved in GlcNAc transport and utilization in . Our previous work confirmed that the chitinase B gene () of strain Bti75 is also negatively controlled by YvoA, the ortholog of NagR from . In this work, we investigated its regulatory network in Bti75 and found that YvoA is an N-acetylglucosamine utilization regulator primarily involved in GlcNAc catabolism; therefore YvoA is renamed as NagR.

α-Melanocyte stimulating hormone (MSH) and prostaglandin E2 (PGE2) drive melanosome transfer by promoting filopodia delivery and shedding spheroid granules: Evidences from atomic force microscopy observation.

Background: Skin pigmentation is accomplished by production of melanin in melanosome and by transfer of these organelles from melanocytes (MCs) to surrounding keratinocytes (KCs). However, the detailed mechanism is still unknown.

Objective: We aimed to investigate the morphological structure changes on human epidermal MCs and KCs, which were either mono-cultured or co-cultured, with or without the treatment of both α-Melanocyte-stimulating hormone (α-MSH) and prostaglandin E2 (PGE2), by atomic force microscopy (AFM) and to provide more direct proofs for process of melanosome transfer.

Acquired localized hypertrichosis induced by internal fixation and plaster cast application.

Hypertrichosis refers to increased vellus hair growth and is independent to androgen excess. The acquired localized hypertrichosis (ALH) is one of the typical hypertrichosis, which mainly results from chronic irritation, inflammation, friction, and occlusion by plaster of Paris. Here, we report a young boy who had ALH on his right hand following a closed fracture with internal fixation and plaster cast application.