Publications by authors named "Hui-Ying Jing"

Aim: Hepatitis B surface antigen (HBsAg) mutant of hepatitis B virus (HBV) is one of the important factors that result in immune escape and cause failure of immunization. In this study we reported and characterized a novel HBV mutant with A-to-G at nt551 and intended to provide theoretical data for prevention of HBV infection in China.

Methods: A methodology comprising polymerase chain reaction (PCR) amplifying, M13 bacteriophage cloning and nucleotide sequencing was used to analyze the sera of the pediatric patient who was hepatitis B (HB) immune failure.

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Synopsis of recent research by authors named "Hui-Ying Jing"

  • - Hui-Ying Jing's recent research primarily focuses on the characterization of hepatitis B virus (HBV) mutants, particularly those that show mutations in the surface antigen gene, which are crucial for understanding immune escape mechanisms.
  • - In the study titled "A novel hepatitis B virus mutant with A-to-G at nt551 in the surface antigen gene," Jing identified a specific HBV mutant that may contribute to vaccine failure and immune evasion in pediatric patients.
  • - The research employed advanced molecular techniques, including PCR amplification and nucleotide sequencing, to analyze patient sera, aiming to provide vital data for improving HBV prevention strategies in China.