Publications by authors named "Hui-Ying Bai"

Article Synopsis
  • Hydrogels are gaining attention for use in artificial muscles and soft robots due to their high water content and responsiveness to stimuli, but traditional hydrogels respond slowly and isotropically, unlike real muscles.
  • New strategies have led to the creation of muscle-like hydrogels featuring oriented nanosheets, enabling them to respond quickly and directionally to changes in temperature through electrostatic repulsion.
  • This review covers the synthesis and mechanisms of these advanced hydrogels, their applications in soft robotics, and outlines potential future challenges and opportunities in the field.
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Objective: To investigate the effects of Xuebijing Injection (, XBJ) on survival rate and pulmonary vasopermeability in a rat model of severe scald injury.

Methods: Rats were divided into two experiments: experiment 1 was monitored for 12 h post-injury for survival analysis after severe burns; in experiment 2, rats were killed for determination of pulmonary vascular permeability and pro-inflflammatory mediators. In both experiments, rats were subject to third-degree 50% total body surface area (TBSA) burns or sham injury followed by XBJ or normal saline (NS) treatment.

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Burn injury may result in multiple organ dysfunction partially because of apoptotic cell death. The authors have previously shown that valproic acid (VPA) improves survival in a dog burn model. The aim of this study is to examine whether a VPA improves survival in a rodent burn model and whether this was because of inhibition of cell apoptosis.

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Background: The aim of this study was to examine whether administration of ulinastatin inhibits pro-inflammatory mediators and ameliorate visceral vasopermeability both in a rat model of major burn, and also in rat cultured endothelial cells stimulated with permeability-evoking mediators.

Methods: Plasma levels of tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), myeloperoxidase (MPO), microvascular permeability, and water content of organ tissues were evaluated in a rodent model of a 55% TBSA full-thickness scald injury. Microvascular permeability was also evaluated with a cultured pulmonary microvascular endothelial cells (PMECs) monolayer after stimulation with trypsin, bradykinin, histamine, prostaglandin E2 and burn serum.

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Objective: To investigate the protection effects of electroacupuncture on injury of lipid peroxidation induced by liver ischemia in septic rats.

Methods: Forty-eight male SD rats were subjected to sepsis induced by cecal ligation and puncture (CLP), and were randomly divided into a Sham operation group (group A), a CLP model group (group B), a CLP model plus electroacupuncture at "Zusanli" (ST 36) group (group C), a CLP model plus electroacupuncture at the shame acupoint (group D), a vagotomy plus CLP model group (group E) and CLP model plus electroacupuncture group after vagotomy (group F), 8 rats in each group. CLP was performed in group E and group F after the abdominal vagotomy.

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Objective: To investigate the effect of carbachol (CAR) on visceral perfusion and lipid oxidation injury in rats with sepsis.

Methods: Sixty-four Sprague-Dawley (SD) rats received cecal ligation and puncture (CLP) surgery, and they were divided randomly into two groups: septic model group (CLP group, n=32) and septic model with CAR-treatment group (CAR group, n=32). CAR (10 microg/kg, CAR group) or normal saline (CLP group) was immediately injected into penial vein.

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Objective: To investigate the protective effect of electro-acupuncturing (EA) at Zusanli point on sepsis induced ischemic and oxygen free radical intestinal injury in rats with sepsis.

Methods: Thirty-two male Wistar rats were used to reproduce sepsis by cecal ligation and puncture (CLP), and they were randomly divided into four groups (each n=8): CLP+EA (CLP/EA), CLP+sham EA (CLP/SEA), vagotomy+CLP+SEA (VA/CLP/SEA) and vagotomy+CLP+EA (VA/CLP/EA). Zusanli point was electro-acupunctured with constant voltage (2-100 Hz,2 mA for 30 minutes) immediately after CLP surgery.

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