Publications by authors named "Hui-Yi Liu"
Article Synopsis
- Parkinson's disease (PD) is linked to the aggregation of α-synuclein (α-syn) and is associated with sleep-wake disorders, particularly in early stages where mechanisms are not well understood.
- Research using transgenic Drosophila models showed that flies overexpressing α-syn experienced excessive daytime sleepiness and difficulties in anticipating activities, alongside identified deficits in specific neurons linked to sleep and circadian rhythm.
- The study found that disrupting lipid metabolism through the inhibition of Sterol Regulatory Element-Binding Protein (SREBP) improved daytime sleep duration in α-syn overexpressing flies, suggesting potential therapeutic strategies for PD-related sleep disturbances.
J Geriatr Cardiol
April 2023
Article Synopsis
- A study conducted in Guangzhou, China, found the overall prevalence of heart failure (HF) among community residents aged 35 and over was 1.06%, with men at a higher risk.
- The research indicated that age, atrial fibrillation, valvular heart disease, and chronic conditions like hypertension significantly increased the odds of developing HF.
- HF incidence was notably higher among individuals aged 65 and above, suggesting that managing existing cardiovascular conditions could help lower the risk of HF in this population.
