Publications by authors named "Hui-Xing Yang"
Fish Shellfish Immunol
April 2019
Article Synopsis
- IL-12Rβ2 is a crucial receptor subunit for IL-12 and IL-35 that influences Th1 cell development and inflammatory responses, but its role in teleost fish is under-researched.
- Researchers cloned and studied the IL-12Rβ2 gene from grass carp, revealing a cDNA of 2875 bp that translates into a 741-amino acid protein with key structural features.
- The study also highlighted IL-12Rβ2's involvement in intestinal inflammation, showing its expression patterns aligned with immune responses during infections, suggesting it plays a regulatory role in fish inflammation.
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