Publications by authors named "Hui-Xian Gu"
Fish Shellfish Immunol
July 2017
Article Synopsis
- The study identifies and characterizes three new variants of piscidin peptides (ecPis-2, ecPis-3, ecPis-4) from the orange-spotted grouper, each with distinct amino acid compositions related to their precursor proteins.
- Phylogenetic analysis suggests that these piscidins are part of a larger family of ancient defense peptides found across various animal groups, indicating their evolutionary significance.
- The synthetic versions of these peptides demonstrate strong antibacterial and antifungal properties, with ecPis-3S showing effectiveness against a specific parasite, and their expression is notably increased in response to bacterial challenges, highlighting their role in the fish's immune response.
