Publications by authors named "Hui-Wen Song"
Article Synopsis
- The analysis aimed to offer insights for addressing multi drug resistant tuberculosis (MDR-TB) by examining its burden, trends, risks, and future projections.
- Researchers utilized the Global Burden of Disease (GBD) 2019 dataset to evaluate key metrics like disability-adjusted life years (DALYs) and mortality, employing various statistical methods to analyze trends and project future incidence.
- Findings revealed that MDR-TB poses a significant health challenge in low socio-demographic regions, particularly affecting older men, with alcohol consumption identified as a major risk factor; urgent strategies are necessary to combat TB by 2030 in these areas.
Objectives: To provide valuable insights for targeted cancer screening among high-risk patients, we analyzed the global and regional burden of neoplasms resulting from alcohol consumption between 1990 and 2019.
Methods: The information used in this study was collected from the Global Burden of Disease 2019 dataset. Initially, the database was used to extract details of mortality rates, disability-adjusted life years (DALYs), and the number of individuals affected by alcohol-related neoplasms (ARNs).
[Effect of BCL11A gene on transcription of γ-globin gene].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2013
This study was aimed to explore the effect of BCL11A gene on transcription of γ-globin gene in K562 cells. B-cell lymphoma/leukemia 11A (BCL11A) gene was silenced by small interfering RNA (siRNA) expression vectors in K562 cells (human erythroblastic leukemia cell line). Gamma-globin mRNA level in K562 cells was determined by RT-PCR.
View Article and Find Full Text PDFBackground And Objective: There is no consensus concerning small bowel preparation before capsule endoscopy (CE). This study evaluated the effects of 4 regimens on small bowel cleansing and diagnostic yield.
Methods: Patients were randomly divided into 4 groups.
[Different splice of the calpain 3 gene in human skeletal muscle tissue and white blood cells].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
June 2010
Objective: To investigate the splice variants of the calpain 3 gene existing in human skeletal muscle tissue and white blood cells, and to explore the feasibility of gene diagnosis using CAPN3 mRNA extracted from peripheral leukocytes.
Methods: Total RNA was extracted from peripheral blood and skeletal muscle tissue in healthy individuals. CAPN3 cDNAs were determined by reverse transcriptase polymerase chain reaction and DNA sequencing.
Clinical Research on the Relation Between Body Mass Index, Motilin and Slow Transit Constipation.
Gastroenterology Res
February 2010
Background: Constipation is a common clinical symptom but its etiology remains unknown. The aims of the study are to discuss the relation between body mass index (BMI), motilin and the slow transit constipation (STC).
Methods: A total of 178 patients with STC and 123 healthy volunteers as controls were divided into three groups according to the BMI, group A (BMI <20), group B (BMI 20-25), and group C (BMI > 25).
[Hypoxia/reoxygenation-induced increased activity and expression of PTP-1B in neonatal rat cardiomyocytes are mediated by nitric oxide].
Zhonghua Xin Xue Guan Bing Za Zhi
August 2008
Objective: To explore if the hypoxia/reoxygenation-induced increased activity and expression of PTP-1B in neonatal rat cardiomyocytes are mediated by nitric oxide (NO).
Methods: Neonatal rat cardiomyocytes were isolated and randomly divided into 4 groups: normal group (N group); hypoxia/reoxygenation group (H/R group); N(omega)-nitro-l-arginine methylester treated group (L-NAME group); hypoxia/reoxygenation plus L-NAME group (L-NA + H/R group). PTP-1B activity in cardiomyocytes was determined spectrophotometrically at 405 nm, PTP-1B expression in cardiomyocytes was detected by Western blot.